Pot, atom and step economic synthesis: a diversity-oriented approach to construct 2-substituted pyrrolo[2,1-f][1,2,4]triazin-4(3H)-ones
文献类型：期刊论文
| 作者 | Xiang, Haoyue; Chen, Yanhong; He, Qian ; Xie, Yuyuan; Yang, Chunhao
|
| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2013 |
| 卷号 | 3期号:17页码:5807-5810 |
| ISSN号 | 2046-2069 |
| DOI | 10.1039/c3ra22909b |
| 文献子类 | Article |
| 英文摘要 | A diversity-oriented approach to construct 2-heteroaryl-substituted pyrrolo[2,1-f][1,2,4]triazin-4(3H)-one derivatives via copper-promoted two-step one pot reactions from chromenone derivatives has been developed. Pot, atom and step economy (PASE) were combined in these sequential reactions, and at least six bonds were formed in one pot. A number of drug-like small molecules were prepared quickly and efficiently. |
| WOS关键词 | KINASE INHIBITORS ; DISCOVERY ; 4(3H)-QUINAZOLINONES ; IDENTIFICATION ; DERIVATIVES ; SERIES ; SAR |
| 资助项目 | Ministry of Science and Technology of China[2012ZX09301001-001] ; Chinese Academy of Sciences ("Interdisciplinary Cooperation Team'' Program for Science and Technology Innovation)[00000000] ; [SKLDR/SIMM(SIMM1105KF-02)] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000316965800013 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/277802]  |
| 专题 | 药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Xiang, Haoyue |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xiang, Haoyue,Chen, Yanhong,He, Qian,et al. Pot, atom and step economic synthesis: a diversity-oriented approach to construct 2-substituted pyrrolo[2,1-f][1,2,4]triazin-4(3H)-ones[J]. RSC ADVANCES,2013,3(17):5807-5810. |
| APA | Xiang, Haoyue,Chen, Yanhong,He, Qian,Xie, Yuyuan,&Yang, Chunhao.(2013).Pot, atom and step economic synthesis: a diversity-oriented approach to construct 2-substituted pyrrolo[2,1-f][1,2,4]triazin-4(3H)-ones.RSC ADVANCES,3(17),5807-5810. |
| MLA | Xiang, Haoyue,et al."Pot, atom and step economic synthesis: a diversity-oriented approach to construct 2-substituted pyrrolo[2,1-f][1,2,4]triazin-4(3H)-ones".RSC ADVANCES 3.17(2013):5807-5810. |
入库方式： OAI收割
来源：上海药物研究所
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