Chemical constituents from Brucea javanica
文献类型:期刊论文
作者 | Dong, Shi-Hui; Liu, Jia![]() ![]() ![]() |
刊名 | PHYTOCHEMISTRY
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出版日期 | 2013-01 |
卷号 | 85页码:175-184 |
关键词 | Brucea javanica Simaroubaceae Triterpenoids Quassinoids Lignans Brujavanones A-N Bruceajavanin C |
ISSN号 | 0031-9422 |
DOI | 10.1016/j.phytochem.2012.08.018 |
文献子类 | Article |
英文摘要 | Fourteen apotirucallane-type triterpenoids, named brujavanones A-N, were isolated from the twigs of Brucea javanica, along with four known quassinoids and seven known lignans from the seeds of B. javanica. Their structures were elucidated on the basis of extensive spectroscopic data analysis. The structure of a previously reported triterpenoid, bruceajavanin C, was revised as its C-21 epimer. The cytotoxic activities of triterpenoids and quassinoids against two human tumor cell lines, HL-60 and A-549, were evaluated, but all the compounds were inactive (IC50 > 10 mu M). (C) 2012 Elsevier Ltd. All rights reserved. |
WOS关键词 | L MERR ; QUASSINOID GLYCOSIDES ; STRUCTURAL ELUCIDATION ; BITTER PRINCIPLES ; MOSAIC-VIRUS ; SEEDS ; LIGNANS ; TRITERPENOIDS ; DERIVATIVES ; GLUCOSIDES |
资助项目 | National Natural Science Foundation[81021062] ; National Natural Science Foundation[20932007] |
WOS研究方向 | Biochemistry & Molecular Biology ; Plant Sciences |
语种 | 英语 |
WOS记录号 | WOS:000314143100020 |
出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
源URL | [http://119.78.100.183/handle/2S10ELR8/277826] ![]() |
专题 | 天然药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
通讯作者 | Yue, Jian-Min |
作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
推荐引用方式 GB/T 7714 | Dong, Shi-Hui,Liu, Jia,Ge, Ying-Zi,et al. Chemical constituents from Brucea javanica[J]. PHYTOCHEMISTRY,2013,85:175-184. |
APA | Dong, Shi-Hui.,Liu, Jia.,Ge, Ying-Zi.,Dong, Lei.,Xu, Cheng-Hui.,...&Yue, Jian-Min.(2013).Chemical constituents from Brucea javanica.PHYTOCHEMISTRY,85,175-184. |
MLA | Dong, Shi-Hui,et al."Chemical constituents from Brucea javanica".PHYTOCHEMISTRY 85(2013):175-184. |
入库方式: OAI收割
来源:上海药物研究所
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