中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Chemical constituents from Brucea javanica

文献类型:期刊论文

作者Dong, Shi-Hui; Liu, Jia; Ge, Ying-Zi; Dong, Lei; Xu, Cheng-Hui; Ding, Jian; Yue, Jian-Min
刊名PHYTOCHEMISTRY
出版日期2013-01
卷号85页码:175-184
关键词Brucea javanica Simaroubaceae Triterpenoids Quassinoids Lignans Brujavanones A-N Bruceajavanin C
ISSN号0031-9422
DOI10.1016/j.phytochem.2012.08.018
文献子类Article
英文摘要Fourteen apotirucallane-type triterpenoids, named brujavanones A-N, were isolated from the twigs of Brucea javanica, along with four known quassinoids and seven known lignans from the seeds of B. javanica. Their structures were elucidated on the basis of extensive spectroscopic data analysis. The structure of a previously reported triterpenoid, bruceajavanin C, was revised as its C-21 epimer. The cytotoxic activities of triterpenoids and quassinoids against two human tumor cell lines, HL-60 and A-549, were evaluated, but all the compounds were inactive (IC50 > 10 mu M). (C) 2012 Elsevier Ltd. All rights reserved.
WOS关键词L MERR ; QUASSINOID GLYCOSIDES ; STRUCTURAL ELUCIDATION ; BITTER PRINCIPLES ; MOSAIC-VIRUS ; SEEDS ; LIGNANS ; TRITERPENOIDS ; DERIVATIVES ; GLUCOSIDES
资助项目National Natural Science Foundation[81021062] ; National Natural Science Foundation[20932007]
WOS研究方向Biochemistry & Molecular Biology ; Plant Sciences
语种英语
WOS记录号WOS:000314143100020
出版者PERGAMON-ELSEVIER SCIENCE LTD
源URL[http://119.78.100.183/handle/2S10ELR8/277826]  
专题天然药物化学研究室
中科院受体结构与功能重点实验室
新药研究国家重点实验室
通讯作者Yue, Jian-Min
作者单位Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China
推荐引用方式
GB/T 7714
Dong, Shi-Hui,Liu, Jia,Ge, Ying-Zi,et al. Chemical constituents from Brucea javanica[J]. PHYTOCHEMISTRY,2013,85:175-184.
APA Dong, Shi-Hui.,Liu, Jia.,Ge, Ying-Zi.,Dong, Lei.,Xu, Cheng-Hui.,...&Yue, Jian-Min.(2013).Chemical constituents from Brucea javanica.PHYTOCHEMISTRY,85,175-184.
MLA Dong, Shi-Hui,et al."Chemical constituents from Brucea javanica".PHYTOCHEMISTRY 85(2013):175-184.

入库方式: OAI收割

来源:上海药物研究所

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