An Organic Molecule Modulated Chemoselective Cyclization of Alkynyl Nitriles Tethered to 2-Alkyl Substituted Chromones with Multireactive Sites
文献类型：期刊论文
| 作者 | Huang, Liping; Liu, Yang; Xie, Fuchun; Hu, Youhong
|
| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2012-12-21 |
| 卷号 | 14期号:24页码:6122-6125 |
| ISSN号 | 1523-7060 |
| DOI | 10.1021/ol302964x |
| 文献子类 | Article |
| 英文摘要 | A small organic molecule phenylacetonitrile promoted chemoselective cyclization of (chromen-3-yl)alkynylnitriles to generate a novel tetracyclic or tricyclic chromone scaffold has been discovered. Importantly, the phenylacetonitrile serves as an anion transfer reagent changing the normal reaction of the substrate. |
| WOS关键词 | PALLADIUM-CATALYZED CARBOANNULATION ; PROPARGYLIC CARBONATES ; INDENE DERIVATIVES ; 5-ENDO-DIG CARBOCYCLIZATION ; ELECTROPHILIC CYCLIZATION ; 1,3-DICARBONYL COMPOUNDS ; EFFICIENT APPROACH ; BETA-KETOESTERS ; TANDEM REACTION ; NUCLEOPHILES |
| 资助项目 | National Natural Science Foundation of China[21172232] ; Ministry of Science and Technology of China[2009CB940903] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000312564500002 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/277840]  |
| 专题 | 药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Hu, Youhong |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Beijing 100864, Peoples R China |
| 推荐引用方式 GB/T 7714 | Huang, Liping,Liu, Yang,Xie, Fuchun,et al. An Organic Molecule Modulated Chemoselective Cyclization of Alkynyl Nitriles Tethered to 2-Alkyl Substituted Chromones with Multireactive Sites[J]. ORGANIC LETTERS,2012,14(24):6122-6125. |
| APA | Huang, Liping,Liu, Yang,Xie, Fuchun,&Hu, Youhong.(2012).An Organic Molecule Modulated Chemoselective Cyclization of Alkynyl Nitriles Tethered to 2-Alkyl Substituted Chromones with Multireactive Sites.ORGANIC LETTERS,14(24),6122-6125. |
| MLA | Huang, Liping,et al."An Organic Molecule Modulated Chemoselective Cyclization of Alkynyl Nitriles Tethered to 2-Alkyl Substituted Chromones with Multireactive Sites".ORGANIC LETTERS 14.24(2012):6122-6125. |
入库方式： OAI收割
来源：上海药物研究所
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