Bioactive natural products from Chinese marine flora and fauna
文献类型:期刊论文
作者 | Zhou, Zhen-fang; Guo, Yue-wei![]() |
刊名 | ACTA PHARMACOLOGICA SINICA
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出版日期 | 2012-09 |
卷号 | 33期号:9页码:1159-1169 |
关键词 | marine natural products biological activity mangrove algae soft coral sponges mollusks |
ISSN号 | 1671-4083 |
DOI | 10.1038/aps.2012.110 |
文献子类 | Review |
英文摘要 | In recent decades, the pharmaceutical application potential of marine natural products has attracted much interest from both natural product chemists and pharmacologists. Our group has long been engaged in the search for bioactive natural products from Chinese marine flora (such as mangroves and algae) and fauna (including sponges, soft corals, and mollusks), resulting in the isolation and characterization of numerous novel secondary metabolites spanning a wide range of structural classes and various biosynthetic origins. Of particular interest is the fact that many of these compounds show promising biological activities, including cytotoxic, antibacterial, and enzyme inhibitory effects. By describing representative studies, this review presents a comprehensive summary regarding the achievements and progress made by our group in the past decade. Several interesting examples are discussed in detail. |
WOS关键词 | MANGROVE BRUGUIERA-GYMNORRHIZA ; DINOFLAGELLATE AMPHIDINIUM SP ; PROBABLE BIOGENETIC PRECURSOR ; MACROCYCLIC POLYDISULFIDE ; POLYHYDROXYL COMPOUND ; PLANT METABOLITES ; METHYL SPONGOATE ; SESQUITERPENES ; SKELETON ; SEA |
资助项目 | National Marine '863' Project[2011AA09070102] ; National Natural Science Foundation of China[21072204] ; National Natural Science Foundation of China[21021063] ; National Natural Science Foundation of China[40976048] ; National Natural Science Foundation of China[31070310] ; National Natural Science Foundation of China[81072572] ; SKLDR/SIMM Projects[SIMM 1203ZZ-03] ; SKLDR/SIMM Projects[SIMM 1105KF-04] ; Syngenta-SIMM-PhD Studentship Project[00000000] ; National ST Major Project[2011ZX09307-002-03] ; EU 7th Framework Programme-IRSES Project[00000000] |
WOS研究方向 | Chemistry ; Pharmacology & Pharmacy |
语种 | 英语 |
CSCD记录号 | CSCD:4635867 |
WOS记录号 | WOS:000308391000008 |
出版者 | ACTA PHARMACOLOGICA SINICA |
源URL | [http://119.78.100.183/handle/2S10ELR8/277964] ![]() |
专题 | 天然药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
通讯作者 | Guo, Yue-wei |
作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
推荐引用方式 GB/T 7714 | Zhou, Zhen-fang,Guo, Yue-wei. Bioactive natural products from Chinese marine flora and fauna[J]. ACTA PHARMACOLOGICA SINICA,2012,33(9):1159-1169. |
APA | Zhou, Zhen-fang,&Guo, Yue-wei.(2012).Bioactive natural products from Chinese marine flora and fauna.ACTA PHARMACOLOGICA SINICA,33(9),1159-1169. |
MLA | Zhou, Zhen-fang,et al."Bioactive natural products from Chinese marine flora and fauna".ACTA PHARMACOLOGICA SINICA 33.9(2012):1159-1169. |
入库方式: OAI收割
来源:上海药物研究所
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