中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Bioactive natural products from Chinese marine flora and fauna

文献类型:期刊论文

作者Zhou, Zhen-fang; Guo, Yue-wei
刊名ACTA PHARMACOLOGICA SINICA
出版日期2012-09
卷号33期号:9页码:1159-1169
关键词marine natural products biological activity mangrove algae soft coral sponges mollusks
ISSN号1671-4083
DOI10.1038/aps.2012.110
文献子类Review
英文摘要In recent decades, the pharmaceutical application potential of marine natural products has attracted much interest from both natural product chemists and pharmacologists. Our group has long been engaged in the search for bioactive natural products from Chinese marine flora (such as mangroves and algae) and fauna (including sponges, soft corals, and mollusks), resulting in the isolation and characterization of numerous novel secondary metabolites spanning a wide range of structural classes and various biosynthetic origins. Of particular interest is the fact that many of these compounds show promising biological activities, including cytotoxic, antibacterial, and enzyme inhibitory effects. By describing representative studies, this review presents a comprehensive summary regarding the achievements and progress made by our group in the past decade. Several interesting examples are discussed in detail.
WOS关键词MANGROVE BRUGUIERA-GYMNORRHIZA ; DINOFLAGELLATE AMPHIDINIUM SP ; PROBABLE BIOGENETIC PRECURSOR ; MACROCYCLIC POLYDISULFIDE ; POLYHYDROXYL COMPOUND ; PLANT METABOLITES ; METHYL SPONGOATE ; SESQUITERPENES ; SKELETON ; SEA
资助项目National Marine '863' Project[2011AA09070102] ; National Natural Science Foundation of China[21072204] ; National Natural Science Foundation of China[21021063] ; National Natural Science Foundation of China[40976048] ; National Natural Science Foundation of China[31070310] ; National Natural Science Foundation of China[81072572] ; SKLDR/SIMM Projects[SIMM 1203ZZ-03] ; SKLDR/SIMM Projects[SIMM 1105KF-04] ; Syngenta-SIMM-PhD Studentship Project[00000000] ; National ST Major Project[2011ZX09307-002-03] ; EU 7th Framework Programme-IRSES Project[00000000]
WOS研究方向Chemistry ; Pharmacology & Pharmacy
语种英语
CSCD记录号CSCD:4635867
WOS记录号WOS:000308391000008
出版者ACTA PHARMACOLOGICA SINICA
源URL[http://119.78.100.183/handle/2S10ELR8/277964]  
专题天然药物化学研究室
中科院受体结构与功能重点实验室
新药研究国家重点实验室
通讯作者Guo, Yue-wei
作者单位Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China
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GB/T 7714
Zhou, Zhen-fang,Guo, Yue-wei. Bioactive natural products from Chinese marine flora and fauna[J]. ACTA PHARMACOLOGICA SINICA,2012,33(9):1159-1169.
APA Zhou, Zhen-fang,&Guo, Yue-wei.(2012).Bioactive natural products from Chinese marine flora and fauna.ACTA PHARMACOLOGICA SINICA,33(9),1159-1169.
MLA Zhou, Zhen-fang,et al."Bioactive natural products from Chinese marine flora and fauna".ACTA PHARMACOLOGICA SINICA 33.9(2012):1159-1169.

入库方式: OAI收割

来源:上海药物研究所

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