Sesquiterpene lactones from Inula cappa
文献类型：期刊论文
| 作者 | Wang, Fang-Yuan1,2; Li, Xi-Qiang1,2; Sun, Qi1,2; Yao, Sheng1,2 ; Ke, Chang-Qiang1,2; Tang, Chun-Ping1,2; Liu, Hong-Chun1,2; Geng, Mei-Yu1,2; Ye, Yang1,2
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| 刊名 | PHYTOCHEMISTRY LETTERS
 |
| 出版日期 | 2012-09 |
| 卷号 | 5期号:3页码:639-642 |
| ISSN号 | 1874-3900 |
| 关键词 | Inula cappa (Buch.-Ham.) DC Compositae Germacranolide Ineupatolides A-C |
| DOI | 10.1016/j.phytol.2012.06.012 |
| 文献子类 | Article |
| 英文摘要 | Three new germacranolides, ineupatolides A-C (1-3), together with six known sesquiterpenoids, were isolated from the aerial parts of Inula cappa (Buch.-Ham.) DC. The structures of new compounds were elucidated by 1D-, and 2D-NMR techniques including HMQC, HMBC, H-1-H-1 COSY and ROESY spectra. The known compounds were identified by spectroscopic data analyses and data comparison. Compound 2 was finally proved to be converted from 1 with the trace existence of acid. Compounds 2 and 5 showed moderate inhibitory activity against human leukemia cell line HL-60, while compounds 2, 5, 6, 7 and 9 exhibited no antiproliferative activities on human lung cancer cell line A549. (C) 2012 Phytochemical Society of Europe. Published by Elsevier B. V. All rights reserved. |
| WOS关键词 | GERMACRANOLIDES ; CYTOTOXICITY |
| 资助项目 | National Science & Technology Major Project "Key New Drug Creation and Manufacturing Program"[2009ZX09103-419] ; National Natural Science Funds for Distinguished Young Scholar[30925043] ; External Cooperation Program of the Chinese Academy of Sciences[GJHZ0939] ; Ministry of Science and Technology[2010DFA30980] ; Shanghai Commission of Science and Technology[00000000] |
| WOS研究方向 | Plant Sciences ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| 出版者 | ELSEVIER SCIENCE BV |
| WOS记录号 | WOS:000307596700050 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/277978]  |
| 专题 | 天然药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Ye, Yang |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, SIMM CUHK Joint Res Lab Promoting Globalizat Trad, Shanghai 201203, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Wang, Fang-Yuan,Li, Xi-Qiang,Sun, Qi,et al. Sesquiterpene lactones from Inula cappa[J]. PHYTOCHEMISTRY LETTERS,2012,5(3):639-642. |
| APA | Wang, Fang-Yuan.,Li, Xi-Qiang.,Sun, Qi.,Yao, Sheng.,Ke, Chang-Qiang.,...&Ye, Yang.(2012).Sesquiterpene lactones from Inula cappa.PHYTOCHEMISTRY LETTERS,5(3),639-642. |
| MLA | Wang, Fang-Yuan,et al."Sesquiterpene lactones from Inula cappa".PHYTOCHEMISTRY LETTERS 5.3(2012):639-642. |
入库方式： OAI收割
来源：上海药物研究所
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