Copper(I)-Mediated Cascade Reactions: An Efficient Approach to the Synthesis of Functionalized Benzofuro[3,2-d]pyrimidines
文献类型：期刊论文
| 作者 | Chao, Bo1; Lin, Shijun1; Ma, Qingdong2; Lu, Dong1; Hu, Youhong1
|
| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2012-05-04 |
| 卷号 | 14期号:9页码:2398-2401 |
| ISSN号 | 1523-7060 |
| DOI | 10.1021/ol300822a |
| 文献子类 | Article |
| 英文摘要 | A novel cascade reaction was developed for the synthesis of diverse members of a series of benzofuro(3,2-d]pyrimidine derivatives. The process utilizes readily prepared 3-chlorochromenones and various commercially available amidines and their analogues as starting materials. This tandem reaction is promoted by using a simple copper(I) reagent and involves a chemoselective Michael addition-heterocyclization-intramolecular cyclization sequence. |
| WOS关键词 | ASYMMETRIC CONJUGATE ADDITION ; ONE-POT SYNTHESIS ; CATALYZED C-N ; ARYL IODIDES ; RECEPTOR ANTAGONISTS ; GRIGNARD-REAGENTS ; FACILE SYNTHESIS ; PRIMARY AMIDES ; COPPER ; 3-COMPONENT |
| 资助项目 | National Natural Science Foundation of China[21172232] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| 出版者 | AMER CHEMICAL SOC |
| WOS记录号 | WOS:000303492200053 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/278081]  |
| 专题 | 药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Hu, Youhong |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; 2.China Univ Petr, Qingdao 266580, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chao, Bo,Lin, Shijun,Ma, Qingdong,et al. Copper(I)-Mediated Cascade Reactions: An Efficient Approach to the Synthesis of Functionalized Benzofuro[3,2-d]pyrimidines[J]. ORGANIC LETTERS,2012,14(9):2398-2401. |
| APA | Chao, Bo,Lin, Shijun,Ma, Qingdong,Lu, Dong,&Hu, Youhong.(2012).Copper(I)-Mediated Cascade Reactions: An Efficient Approach to the Synthesis of Functionalized Benzofuro[3,2-d]pyrimidines.ORGANIC LETTERS,14(9),2398-2401. |
| MLA | Chao, Bo,et al."Copper(I)-Mediated Cascade Reactions: An Efficient Approach to the Synthesis of Functionalized Benzofuro[3,2-d]pyrimidines".ORGANIC LETTERS 14.9(2012):2398-2401. |
入库方式： OAI收割
来源：上海药物研究所
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