Yalongenes A and B, Two New Cembranoids with Cytoprotective Effects from the Hainan Soft Coral Sarcophyton trocheliophorum Marenzeller
文献类型：期刊论文
| 作者 | Yao, Li-Gong2; Zhang, Hai-Yan2 ; Liang, Lin-Fu2; Guo, Xian-Jun2; Mao, Shui-Chun1; Guo, Yue-Wei2
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| 刊名 | HELVETICA CHIMICA ACTA
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| 出版日期 | 2012-02 |
| 卷号 | 95期号:2页码:235-239 |
| 关键词 | Sarcophyton trocheliophorum Cembranoids Yalongenes A and B Cytoprotective activity Soft corals |
| ISSN号 | 0018-019X |
| DOI | 10.1002/hlca.201100278 |
| 文献子类 | Article |
| 英文摘要 | Two new cembranoids, yalongenes A (1) and B (2), were isolated from the South China Sea soft coral Sarcophyton trocheliophorum Marenzeller. Their structures were elucidated by detailed spectroscopic analysis (IR, MS, and NMR) and by comparison with a related model compound. Yalongenes 1 and 2 were evaluated for their cytoprotective effects on SH-SY5Y cell injury induced by H2O2 in vitro, and the result showed that only compound 1 had a significant cytoprotective activity at the concentration of 1 mu M. |
| WOS关键词 | BISABOLENE-TYPE SESQUITERPENES ; PROBABLE BIOGENETIC PRECURSOR ; VARIABILIS ; LATUM |
| 资助项目 | National Science & Technology Major Project[2009ZX09301-001] ; National Marine 863 Project[2011AA09070102] ; Natural Science Foundation of China[21072204] ; Natural Science Foundation of China[30730108] ; Natural Science Foundation of China[21021063] ; NSFC-TRF[20911140471] ; STCSM between SIMM/China and ICB/Italy[10540702900] ; Hungarian-Chinese Intergovernmental S&T Cooperation Programme[00000000] ; EU 7th Framework Programme-IRSES Project[00000000] ; SIMM-SKLDR[KSCX2-YW-R-18] ; SIMM-SKLDR[SIMM1105KF-04] ; SIMM-SKLDR[SIMM1106KF-11] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000300665700007 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/278191]  |
| 专题 | 天然药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Mao, Shui-Chun |
| 作者单位 | 1.Nanchang Univ, Dept Pharm, Nanchang 330006, Peoples R China; 2.Chinese Acad Sci, State Key Lab Drug Res, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yao, Li-Gong,Zhang, Hai-Yan,Liang, Lin-Fu,et al. Yalongenes A and B, Two New Cembranoids with Cytoprotective Effects from the Hainan Soft Coral Sarcophyton trocheliophorum Marenzeller[J]. HELVETICA CHIMICA ACTA,2012,95(2):235-239. |
| APA | Yao, Li-Gong,Zhang, Hai-Yan,Liang, Lin-Fu,Guo, Xian-Jun,Mao, Shui-Chun,&Guo, Yue-Wei.(2012).Yalongenes A and B, Two New Cembranoids with Cytoprotective Effects from the Hainan Soft Coral Sarcophyton trocheliophorum Marenzeller.HELVETICA CHIMICA ACTA,95(2),235-239. |
| MLA | Yao, Li-Gong,et al."Yalongenes A and B, Two New Cembranoids with Cytoprotective Effects from the Hainan Soft Coral Sarcophyton trocheliophorum Marenzeller".HELVETICA CHIMICA ACTA 95.2(2012):235-239. |
入库方式： OAI收割
来源：上海药物研究所
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