Tritoniopsins A-D, Cladiellane-Based Diterpenes from the South China Sea Nudibranch Tritoniopsis elegans and Its Prey Cladiella krempfi
文献类型：期刊论文
| 作者 | Ciavatta, Maria Letizia1; Manzo, Emiliano1; Mollo, Ernesto1; Mattia, Carlo Andrea2; Tedesco, Consiglia3; Irace, Carlo4; Guo, Yue-Wei5 ; Li, Xiu-Bao6; Cimino, Guido1; Gavagnin, Margherita1
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| 刊名 | JOURNAL OF NATURAL PRODUCTS
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| 出版日期 | 2011-09 |
| 卷号 | 74期号:9页码:1902-1907 |
| ISSN号 | 0163-3864 |
| DOI | 10.1021/np200342k |
| 文献子类 | Article |
| 英文摘要 | Four diterpenes, tritoniopsins A-D (1-4), have been isolated from the South China Sea nudibranch Tritoniopsis elegans and its prey, the soft coral Cladiella krempfi. They display an unprecedented pyran ring in the cladiellane framework, thus representing a novel cladiellane-based diterpene family. Their structures have been mainly characterized by NMR and mass spectrometric techniques, whereas the relative configuration of compound 1 was secured by X-ray analysis. Antiproliferative assays on tumor and nontumor cell lines have been carried out for the main metabolite, tritoniopsin B (2). |
| WOS关键词 | EUNICELLIN-BASED DITERPENOIDS ; ABSOLUTE-CONFIGURATIONS ; MOSHER METHOD ; CORAL ; ASTROGORGIN ; TERPENOIDS |
| 资助项目 | S & T Major Project[2009ZX09301-001] ; National Marine 863 Project[2011AA090071-2] ; NSFC[30730108] ; NSFC[21021063] ; NSFC[21072204] ; CAS[KSX2-YW-R-18] ; STCSM[10540702900] ; MIUR[00000000] |
| WOS研究方向 | Plant Sciences ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000295100400010 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/278419]  |
| 专题 | 天然药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Ciavatta, Maria Letizia |
| 作者单位 | 1.Ist Chim Biomol ICB CNR, I-80078 Naples, Italy; 2.Univ Salerno, Dipartimento Sci Farmaceut, I-84084 Fisciano, Sa, Italy; 3.Univ Salerno, Dipartimento Chim, I-84084 Fisciano, Sa, Italy; 4.Univ Naples Federico 2, Dipartimento Farmacol Sperimentale, I-80131 Naples, Italy; 5.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; 6.Chinese Acad Sci, S China Sea Inst Oceanol, Guangzhou 510301, Guangdong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ciavatta, Maria Letizia,Manzo, Emiliano,Mollo, Ernesto,et al. Tritoniopsins A-D, Cladiellane-Based Diterpenes from the South China Sea Nudibranch Tritoniopsis elegans and Its Prey Cladiella krempfi[J]. JOURNAL OF NATURAL PRODUCTS,2011,74(9):1902-1907. |
| APA | Ciavatta, Maria Letizia.,Manzo, Emiliano.,Mollo, Ernesto.,Mattia, Carlo Andrea.,Tedesco, Consiglia.,...&Gavagnin, Margherita.(2011).Tritoniopsins A-D, Cladiellane-Based Diterpenes from the South China Sea Nudibranch Tritoniopsis elegans and Its Prey Cladiella krempfi.JOURNAL OF NATURAL PRODUCTS,74(9),1902-1907. |
| MLA | Ciavatta, Maria Letizia,et al."Tritoniopsins A-D, Cladiellane-Based Diterpenes from the South China Sea Nudibranch Tritoniopsis elegans and Its Prey Cladiella krempfi".JOURNAL OF NATURAL PRODUCTS 74.9(2011):1902-1907. |
入库方式： OAI收割
来源：上海药物研究所
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