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New dibenzocyclooctadiene lignans from the Kadsura ananosma

文献类型：期刊论文

作者Yang, Jian-Hong1,4; Zhang, Hai-Yan2; Du, Xue1; Wang, Wei2; Xiao, Wei-Lie1; Wen, Jin3; Pu, Jian-Xin1; Tang, Xi-Can2; Sun, Han-Dong1
刊名TETRAHEDRON
出版日期2011-06-24
卷号67期号:25页码:4498-4504
关键词Kadsura ananosma Dibenzocyclooctadiene lignans Ananonins Neuroprotective effect
ISSN号0040-4020
DOI10.1016/j.tet.2011.04.105
文献子类Article
英文摘要Fourteen new dibenzocyclooctadiene lignans, ananonins A-N (1-14), together with five known compounds, were isolated from the seeds of Kadsura ananosma. The structures and absolute configurations of 1-14 were established using a combination of MS, NMR, and CD techniques. The biological activity of these compounds was evaluated, and ananonin M (13) showed moderate neuroprotective effects in an in vitro assay. (C) 2011 Elsevier Ltd. All rights reserved.
WOS关键词C-19 HOMOLIGNANS ; GOMISIN-G ; HETEROCLITA ; INTERIOR ; CELLS ; TRITERPENOIDS ; PROTECTS ; STEMS
资助项目NSFC[30830115] ; NSFC[20902093] ; Science and Technology Program of Yunnan Province[2008GA031] ; Major State Basic Research Development Program of China[2009CB522300] ; Major State Basic Research Development Program of China[200940900] ; Western Doctoral Foundation of Chinese Academy of Sciences[00000000] ; CAS[KZCX2-XB2-15] ; National Science & Technology Major Project 'Key New Drug Creation and Manufacturing Program of China'[2009ZX09301-001] ; National Science & Technology Major Project 'Key New Drug Creation and Manufacturing Program of China'[063]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000291778000003
出版者PERGAMON-ELSEVIER SCIENCE LTD
源URL[http://119.78.100.183/handle/2S10ELR8/278495]  
专题药理学第二研究室
中科院受体结构与功能重点实验室
新药研究国家重点实验室
院士及顾问专家
通讯作者Pu, Jian-Xin
作者单位1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China;
2.Chinese Acad Sci, State Key Lab Drug Res, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China;
3.Yunnan Acad Forest Sci, Inst Trop Forestry, Kunming 650204, Peoples R China;
4.Acad Sci, Grad Univ Chinese, Beijing 100039, Peoples R China
推荐引用方式
GB/T 7714		 Yang, Jian-Hong,Zhang, Hai-Yan,Du, Xue,et al. New dibenzocyclooctadiene lignans from the Kadsura ananosma[J]. TETRAHEDRON,2011,67(25):4498-4504.
APA Yang, Jian-Hong.,Zhang, Hai-Yan.,Du, Xue.,Wang, Wei.,Xiao, Wei-Lie.,...&Sun, Han-Dong.(2011).New dibenzocyclooctadiene lignans from the Kadsura ananosma.TETRAHEDRON,67(25),4498-4504.
MLA Yang, Jian-Hong,et al."New dibenzocyclooctadiene lignans from the Kadsura ananosma".TETRAHEDRON 67.25(2011):4498-4504.

入库方式： OAI收割

来源：上海药物研究所

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