Dibenzocyclooctadiene Lignans with Antineurodegenerative Potential from Kadsura ananosma
文献类型：期刊论文
| 作者 | Yang, Jian-Hong1,5; Zhang, Hai-Yan2 ; Wen, Jin3; Du, Xue1; Chen, Jian-Hua4; Zhang, Hai-Bo1; Xiao, Wei-Lie1; Pu, Jian-Xin1; Tang, Xi-Can2; Sun, Han-Dong1
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| 刊名 | JOURNAL OF NATURAL PRODUCTS
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| 出版日期 | 2011-05 |
| 卷号 | 74期号:5页码:1028-1035 |
| ISSN号 | 0163-3864 |
| DOI | 10.1021/np1009288 |
| 文献子类 | Article |
| 英文摘要 | Fourteen new dibenzocyclooctadiene lignans, ananolignans A-N (1-14), together with five known compounds, were isolated from the seeds of Kadsura ana iosma. The structures and absolute configurations of 1-14 were established using a combination of spectroscopic methods including 1D- and 2D-NMR and CD techniques. The biological activity of the isolated lignans was evaluated, and ananolignan F (6) and ananolignan L (12) showed significant neuroprotective effects in an in vitro assay. |
| WOS关键词 | SCHIZANDRA-CHINENSIS BAILL ; GOMISIN-G ; INTERIOR ; CELLS ; PHILIPPINENSIS ; CONSTITUENTS ; COCCINEA ; PROTECTS |
| 资助项目 | NSFC[30830115] ; NSFC[20902093] ; Science and Technology Program of Yunan Province[2008GA031] ; Major State Basic Research Development Program of China[2009CB522300] ; Major State Basic Research Development Program of China[200940900] ; Western Doctoral Foundation of Chinese Academy of Sciences[KZCX2-XB2-15] ; National Science & Technology Major Project "Key New Drug Creation and Manufacturing Program of China"[2009ZX09301-001] ; National Science & Technology Major Project "Key New Drug Creation and Manufacturing Program of China"[-063] |
| WOS研究方向 | Plant Sciences ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| 出版者 | AMER CHEMICAL SOC |
| WOS记录号 | WOS:000291127900017 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/278536]  |
| 专题 | 药理学第二研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 院士及顾问专家 |
| 通讯作者 | Pu, Jian-Xin |
| 作者单位 | 1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China; 2.Chinese Acad Sci, State Key Lab Drug Res, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China; 3.Inst Trop Forestry, Yunnan Acad Forest Sci, Kunming 650204, Peoples R China; 4.Yunnan Acad Tobacco Sci, Kunming 650106, Peoples R China; 5.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, Jian-Hong,Zhang, Hai-Yan,Wen, Jin,et al. Dibenzocyclooctadiene Lignans with Antineurodegenerative Potential from Kadsura ananosma[J]. JOURNAL OF NATURAL PRODUCTS,2011,74(5):1028-1035. |
| APA | Yang, Jian-Hong.,Zhang, Hai-Yan.,Wen, Jin.,Du, Xue.,Chen, Jian-Hua.,...&Sun, Han-Dong.(2011).Dibenzocyclooctadiene Lignans with Antineurodegenerative Potential from Kadsura ananosma.JOURNAL OF NATURAL PRODUCTS,74(5),1028-1035. |
| MLA | Yang, Jian-Hong,et al."Dibenzocyclooctadiene Lignans with Antineurodegenerative Potential from Kadsura ananosma".JOURNAL OF NATURAL PRODUCTS 74.5(2011):1028-1035. |
入库方式： OAI收割
来源：上海药物研究所
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