Palmarumycins BG1-BG7 and Preussomerin BG1: Establishment of Their Absolute Configurations Using Theoretical Calculations of Electronic Circular Dichroisnn Spectra
文献类型：期刊论文
| 作者 | Cai, You-Sheng1; Kurtan, Tibor2; Ze-Hong Miao1; Mandi, Attila3; Komaromi, Istvan4; Liu, Hai-Li1; Ding, Jian1 ; Guo, Yue-Wei1
|
| 刊名 | JOURNAL OF ORGANIC CHEMISTRY
 |
| 出版日期 | 2011-03-18 |
| 卷号 | 76期号:6页码:1821-1830 |
| ISSN号 | 0022-3263 |
| DOI | 10.1021/jo1024877 |
| 文献子类 | Article |
| 英文摘要 | Palmarumycins BG1-BG7 (1-7), seven new compounds related to palmarumycins, were isolated from the aerial parts of Bruguiera gymnorrhiza as well as a new preussomerin derivative BG1 (8). The structures of these compounds were determined mainly by the analysis of their NMR and MS data, and their relative configurations were assigned on the basis of their (3)J(H,H) coupling constants. Compounds 4 and 7 have a sulfate group that is unprecedented among members of spirodioxynaphthalene-type natural products. The absolute configurations of 1-8 were determined by TDDFT CD calculations of the solution conformers. Compound 5 displayed inhibitory activity against HL 60 and MCF-7 cell lines. |
| WOS关键词 | MANGROVE BRUGUIERA-GYMNORRHIZA ; BIOLOGICALLY-ACTIVE METABOLITES ; FUNGUS NATTRASSIA-MANGIFERAE ; MACROCYCLIC POLYDISULFIDE ; STRUCTURE ELUCIDATION ; SECONDARY METABOLITES ; PLANT METABOLITES ; ENDOPHYTIC FUNGUS ; PREUSSIA-ISOMERA ; DEOXYPREUSSOMERINS |
| 资助项目 | National S & T Major Project[2009ZX09301-001] ; National S & T Major Project[2009ZX09103-060] ; National Marine 863 Program for Druggability Evaluation[00000000] ; Natural Science Foundation of China[30730108] ; Natural Science Foundation of China[21021063] ; Natural Science Foundation of China[0976048] ; Natural Science Foundation of China[81072572] ; STCSM Project[09ZR1438000] ; STCSM Project[10540702900] ; CAS[SIMM0907KF-09] ; CAS[KSCX2-YW-R-18] ; EU[00000000] ; National Office for Research and Technology (NKTH)[K-68429] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000288142800035 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/278581]  |
| 专题 | 天然药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 药理学第一研究室 |
| 通讯作者 | Kurtan, Tibor |
| 作者单位 | 1.Chinese Acad Sci, State Key Lab Drug Res, Inst Mat Med, Shanghai 201203, Peoples R China; 2.Univ Debrecen, Dept Organ Chem, H-4010 Debrecen, Hungary; 3.Univ Debrecen, Hungarian Acad Sci, Res Grp Carbohydrates, H-4010 Debrecen, Hungary; 4.Univ Debrecen, Hungarian Acad Sci, Thrombosis Hemostasis & Vasc Biol Res Grp, H-4032 Debrecen, Hungary |
| 推荐引用方式 GB/T 7714 | Cai, You-Sheng,Kurtan, Tibor,Ze-Hong Miao,et al. Palmarumycins BG1-BG7 and Preussomerin BG1: Establishment of Their Absolute Configurations Using Theoretical Calculations of Electronic Circular Dichroisnn Spectra[J]. JOURNAL OF ORGANIC CHEMISTRY,2011,76(6):1821-1830. |
| APA | Cai, You-Sheng.,Kurtan, Tibor.,Ze-Hong Miao.,Mandi, Attila.,Komaromi, Istvan.,...&Guo, Yue-Wei.(2011).Palmarumycins BG1-BG7 and Preussomerin BG1: Establishment of Their Absolute Configurations Using Theoretical Calculations of Electronic Circular Dichroisnn Spectra.JOURNAL OF ORGANIC CHEMISTRY,76(6),1821-1830. |
| MLA | Cai, You-Sheng,et al."Palmarumycins BG1-BG7 and Preussomerin BG1: Establishment of Their Absolute Configurations Using Theoretical Calculations of Electronic Circular Dichroisnn Spectra".JOURNAL OF ORGANIC CHEMISTRY 76.6(2011):1821-1830. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。