Ring A-seco triterpenoids with antibacterial activity from Dysoxylum hainanense
文献类型：期刊论文
| 作者 | He, Xiu-Feng; Wang, Xiao-Ning; Yin, Sheng; Dong, Lei; Yue, Jian-Min
|
| 刊名 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
 |
| 出版日期 | 2011-01 |
| 卷号 | 21期号:1页码:125-129 |
| 关键词 | Dysoxylum hainanense Triterpenoids Structural elucidation Antibacterial activity Structure-activity relationship |
| ISSN号 | 0960-894X |
| DOI | 10.1016/j.bmcl.2010.11.057 |
| 文献子类 | Article |
| 英文摘要 | Five new ring A-seco triterpenoids, dysoxyhainic acids F-J (1-5), along with a known ring A-seco triterpenoid koetjapic acid (6) were isolated from the twigs and leaves of Dysoxylum hainanense. Their structures were established on the basis of extensive spectroscopic analysis. Antimicrobial activity of all the compounds against fungi and bacteria were tested. Compounds 2-4 and 6 exhibited significant antimicrobial activity against Gram-positive bacteria, and the antibacterial SAR (structure-activity relationship) was also briefly discussed. (C) 2010 Elsevier Ltd. All rights reserved. |
| WOS关键词 | AGENTS ; LIMONOIDS |
| 资助项目 | National Natural Science Foundation[30701044] ; National Natural Science Foundation[21072203] ; Chinese Academy of Sciences[KSCX2-YW-R-117] ; Chinese Academy of Sciences[KSCX2-YW-R-184)] ; National Science & Technology Major Project 'Key New Drug Creation and Manufacturing Program' of the People's Republic of China[2009ZX09301-001] |
| WOS研究方向 | Pharmacology & Pharmacy ; Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000285544400020 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/278636]  |
| 专题 | 天然药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Yue, Jian-Min |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | He, Xiu-Feng,Wang, Xiao-Ning,Yin, Sheng,et al. Ring A-seco triterpenoids with antibacterial activity from Dysoxylum hainanense[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2011,21(1):125-129. |
| APA | He, Xiu-Feng,Wang, Xiao-Ning,Yin, Sheng,Dong, Lei,&Yue, Jian-Min.(2011).Ring A-seco triterpenoids with antibacterial activity from Dysoxylum hainanense.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,21(1),125-129. |
| MLA | He, Xiu-Feng,et al."Ring A-seco triterpenoids with antibacterial activity from Dysoxylum hainanense".BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 21.1(2011):125-129. |
入库方式： OAI收割
来源：上海药物研究所
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