中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 上海药物研究所
  3. 中国科学院上海药物研究所
  4. 国家新药筛选中心
Synthesis and revision of stereochemistry of rubescensin S

文献类型：期刊论文

作者Zhang, Mei1,2,3; Zhang, Yangming3; Lu, Wei1,2; Nan, Fa-Jun3
刊名ORGANIC & BIOMOLECULAR CHEMISTRY
出版日期2011
卷号9期号:12页码:4436-4439
ISSN号1477-0520
DOI10.1039/c1ob05611e
文献子类Article
英文摘要An effective two step transformation of oridonin to 15,16-seco-ent-kaurane skeleton is reported. We also achieved the conversion of one intermediate to natural product rubescensin S and revised its structure as a 13S configuration although 13R is reported in the literature.
WOS关键词ANTIBACTERIAL ACTIVITY ; ISODON DITERPENOIDS ; WEINREB AMIDES ; CONVERSION ; DISCOVERY ; ANTITUMOR ; CHEMISTRY
资助项目National Natural Science Foundation of China[30725049] ; National Natural Science Foundation of China[81021062] ; National Science & Technology Major Project "Key New Drug Creation and Manufacturing Program", China[2009ZX09301-001] ; National Science & Technology Major Project "Key New Drug Creation and Manufacturing Program", China[2009ZX09302-001]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000291218900007
出版者ROYAL SOC CHEMISTRY
源URL[http://119.78.100.183/handle/2S10ELR8/278671]  
专题国家新药筛选中心
中科院受体结构与功能重点实验室
新药研究国家重点实验室
通讯作者Lu, Wei
作者单位1.E China Normal Univ, Dept Chem, Shanghai 200062, Peoples R China;
2.E China Normal Univ, Inst Med Chem, Shanghai 200062, Peoples R China;
3.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Chinese Natl Ctr Drug Screening, Shanghai 201203, Peoples R China
推荐引用方式
GB/T 7714		 Zhang, Mei,Zhang, Yangming,Lu, Wei,et al. Synthesis and revision of stereochemistry of rubescensin S[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2011,9(12):4436-4439.
APA Zhang, Mei,Zhang, Yangming,Lu, Wei,&Nan, Fa-Jun.(2011).Synthesis and revision of stereochemistry of rubescensin S.ORGANIC & BIOMOLECULAR CHEMISTRY,9(12),4436-4439.
MLA Zhang, Mei,et al."Synthesis and revision of stereochemistry of rubescensin S".ORGANIC & BIOMOLECULAR CHEMISTRY 9.12(2011):4436-4439.

入库方式： OAI收割

来源：上海药物研究所

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。