Three-Component One-Pot Approach to Synthesize Benzopyrano[4,3-d]pyrimidines
文献类型:期刊论文
| 作者 | Li, Dewen; Duan, Shudong; Hu, Youhong
|
| 刊名 | JOURNAL OF COMBINATORIAL CHEMISTRY
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| 出版日期 | 2010-11 |
| 卷号 | 12期号:6页码:895-899 |
| ISSN号 | 1520-4766 |
| DOI | 10.1021/cc100173b |
| 文献子类 | Article |
| 英文摘要 | A novel benzopyrano[4,3-d]pyrimidine scaffold was generated via a three-component one-pot reaction from iodochromone, alkyne, and an amidine through a Sonogashira coupling, condensation, and cycloaddition. This combinatorial synthetic approach provides an efficient, easy construction of a diversified heterocyclic compounds library. |
| WOS关键词 | PHARMACOLOGICAL EVALUATION ; MULTICOMPONENT SYNTHESES ; ORGANIC-SYNTHESIS ; HETEROCYCLES ; DERIVATIVES ; GENERATION ; ALKYNONES ; AMIDINES ; AGENTS |
| 资助项目 | National Science & Technology Major Project "Key New Drug Creation and Manufacturing Program"[2009ZX-09301-001] ; National Natural Science Foundation of China[30873142] |
| WOS研究方向 | Chemistry ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000283810600015 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/278740] ![]() |
| 专题 | 药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Hu, Youhong |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Dewen,Duan, Shudong,Hu, Youhong. Three-Component One-Pot Approach to Synthesize Benzopyrano[4,3-d]pyrimidines[J]. JOURNAL OF COMBINATORIAL CHEMISTRY,2010,12(6):895-899. |
| APA | Li, Dewen,Duan, Shudong,&Hu, Youhong.(2010).Three-Component One-Pot Approach to Synthesize Benzopyrano[4,3-d]pyrimidines.JOURNAL OF COMBINATORIAL CHEMISTRY,12(6),895-899. |
| MLA | Li, Dewen,et al."Three-Component One-Pot Approach to Synthesize Benzopyrano[4,3-d]pyrimidines".JOURNAL OF COMBINATORIAL CHEMISTRY 12.6(2010):895-899. |
入库方式: OAI收割
来源:上海药物研究所
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