One-Pot AgOAc-Mediated Synthesis of Polysubstituted Pyrroles from Primary Amines and Aldehydes: Application to the Total Synthesis of Purpurone
文献类型：期刊论文
| 作者 | Li, Qingjiang1; Fan, Aili1; Lu, Zhiyao1; Cui, Yuxin1; Lin, Wenhan1; Jia, Yanxing1,2 |
| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2010-09-17 |
| 卷号 | 12期号:18页码:4066-4069 |
| ISSN号 | 1523-7060 |
| DOI | 10.1021/ol101644g |
| 文献子类 | Article |
| 英文摘要 | A simple and efficient method for the synthesis of 1,3,4-trisubstituted or 3,4-disubstituted pyrroles has been developed. The reaction represents the first time that pyrroles are synthesized directly from readily available aldehydes and amines (anilines) as starting materials. This method has been successfully applied to the rapid synthesis of purpurone. |
| WOS关键词 | EFFICIENT TOTAL-SYNTHESIS ; C BOND FORMATION ; N-ARYL ENAMINES ; LEAD-TETRAACETATE ; SUBSTITUTED PYRROLES ; SEQUENTIAL REACTIONS ; COUPLING REACTIONS ; DIRECT ANNULATION ; ALPHA-ARYLATION ; OXIDATION |
| 资助项目 | National Basic Research Program of China (973 Program)[2010CB833200] ; State Key Laboratory of Drug Research[00000000] ; National Natural Science Foundation of China[20972007] ; National Natural Science Foundation of China[20802005] ; National Natural Science Foundation of China[30930109] ; NCET[00000000] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000281596800027 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/278773]  |
| 专题 | 新药研究国家重点实验室 中科院受体结构与功能重点实验室 |
| 通讯作者 | Jia, Yanxing |
| 作者单位 | 1.Peking Univ, State Key Lab Nat & Biomimet Drugs, Sch Pharmaceut Sci, Beijing 100191, Peoples R China; 2.Chinese Acad Sci, State Key Lab Drug Res, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Qingjiang,Fan, Aili,Lu, Zhiyao,et al. One-Pot AgOAc-Mediated Synthesis of Polysubstituted Pyrroles from Primary Amines and Aldehydes: Application to the Total Synthesis of Purpurone[J]. ORGANIC LETTERS,2010,12(18):4066-4069. |
| APA | Li, Qingjiang,Fan, Aili,Lu, Zhiyao,Cui, Yuxin,Lin, Wenhan,&Jia, Yanxing.(2010).One-Pot AgOAc-Mediated Synthesis of Polysubstituted Pyrroles from Primary Amines and Aldehydes: Application to the Total Synthesis of Purpurone.ORGANIC LETTERS,12(18),4066-4069. |
| MLA | Li, Qingjiang,et al."One-Pot AgOAc-Mediated Synthesis of Polysubstituted Pyrroles from Primary Amines and Aldehydes: Application to the Total Synthesis of Purpurone".ORGANIC LETTERS 12.18(2010):4066-4069. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。