Retrospect and prospect of active principles from Chinese herbs in the treatment of dementia
文献类型：期刊论文
| 作者 | Wang, Ying2; Huang, Lu-qi1; Tang, Xi-can2 ; Zhang, Hai-yan2
|
| 刊名 | ACTA PHARMACOLOGICA SINICA
 |
| 出版日期 | 2010-06 |
| 卷号 | 31期号:6页码:649-664 |
| 关键词 | dementia traditional Chinese medicine (TCM) active principle neuroprotection |
| ISSN号 | 1671-4083 |
| DOI | 10.1038/aps.2010.46 |
| 文献子类 | Review |
| 英文摘要 | With an ageing population, dementia has become one of the world's primary health challenges. However, existing remedies offer limited benefits with certain side effects, which has prompted researchers to seek complementary and alternative therapies. China has long been known for abundant usage of various herbs. Some of these herbal decoctions are effective in stimulating blood circulation, supplementing vital energy and resisting aging, the lack of which are believed to underlie dementia. These herbs are regarded as new and promising sources of potential anti-dementia drugs. With the rapid evolution of life science and technology, numerous active components have been identified that are highly potent and multi-targeted with low toxicity, and therefore meet the requirements for dementia therapy. This review updates the research progress of Chinese herbs in the treatment of dementia, focusing on their effective principles. |
| WOS关键词 | ALZHEIMER TRANSGENIC MICE ; FOCAL CEREBRAL-ISCHEMIA ; GINKGO-BILOBA EXTRACT ; GREEN TEA ; OXIDATIVE STRESS ; SALVIA-OFFICINALIS ; HUPERZINE-B ; FERULIC ACID ; DOUBLE-BLIND ; IN-VITRO |
| 资助项目 | Ministry of Science and Technology of China[G199805110] ; Ministry of Science and Technology of China[G1998051115] ; Ministry of Science and Technology of China[2004CB518907] ; National Science & Technology, Major Project "Key New Drug Creation and Manufacturing Program" China[2009ZX09103-063] ; National Natural Science Foundation of China[39170860] ; National Natural Science Foundation of China[39770846] ; National Natural Science Foundation of China[3001161954] ; National Natural Science Foundation of China[30123005] ; National Natural Science Foundation of China[30271494] ; National Natural Science Foundation of China[30572169] ; National Natural Science Foundation of China[30801402] |
| WOS研究方向 | Chemistry ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| CSCD记录号 | CSCD:3893596 |
| WOS记录号 | WOS:000278341900001 |
| 出版者 | ACTA PHARMACOLOGICA SINICA |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/278878]  |
| 专题 | 药理学第二研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 药物化学研究室 |
| 通讯作者 | Zhang, Hai-yan |
| 作者单位 | 1.China Acad Chinese Med Sci, Inst Chinese Mat Med, Beijing 100700, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Wang, Ying,Huang, Lu-qi,Tang, Xi-can,et al. Retrospect and prospect of active principles from Chinese herbs in the treatment of dementia[J]. ACTA PHARMACOLOGICA SINICA,2010,31(6):649-664. |
| APA | Wang, Ying,Huang, Lu-qi,Tang, Xi-can,&Zhang, Hai-yan.(2010).Retrospect and prospect of active principles from Chinese herbs in the treatment of dementia.ACTA PHARMACOLOGICA SINICA,31(6),649-664. |
| MLA | Wang, Ying,et al."Retrospect and prospect of active principles from Chinese herbs in the treatment of dementia".ACTA PHARMACOLOGICA SINICA 31.6(2010):649-664. |
入库方式： OAI收割
来源：上海药物研究所
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