Susceptibilities of Mycoplasma and ureaplasma to derivatives (YH16, YH17) of sparfloxacin in vitro
文献类型：期刊论文
| 作者 | Ye Hui1; Yang Yushe2 ; Xie Huansong1; Wu Jimin2; Chen Kaixian2; Ji Ruyuan1
|
| 刊名 | Chinese Journal of Antibiotics
 |
| 出版日期 | 2003 |
| 卷号 | 28期号:8页码:494-496 |
| 关键词 | mycoplasma hominis ureaplasma urealyticum microbial sensitivity sparfloxacin derivative structure-activity relationship |
| ISSN号 | 1001-8689 |
| 其他题名 | 司帕沙星衍生物（YH16，YH17）体外抗枝原体活性研究 |
| 文献子类 | Article |
| 英文摘要 | To evaluate the susceptibilities of Mycoplasma and Ureaplasma to derivatives (YH16 and YH17) of sparfloxacin by microdilution method in vitro in comparison with sparfloxacin. Results show that the minimum inhibition, concentration (MIC_(90)) of YH16 and YH17 against Ureaplasma urealyticum (Uu) (1.0 and 0.5 mg/L), and Mycoplasma hominis (Mh) (0.25 and 0.125mg/L), were 1/8~1/16 those of sparfloxacin against Mh, and 1/4～1/8 those of sparfloxacin against Uu. However, there were cross resistance YH16 and YH17 for Uu and Mh strains resistant to other quinolones. |
| 资助项目 | 国家自然科学基金（No. 29672037）资助项目[00000000] |
| WOS研究方向 | Pharmacology & Pharmacy (provided by Clarivate Analytics) |
| 语种 | 中文 |
| CSCD记录号 | CSCD:1254765 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/268433]  |
| 专题 | 药物化学研究室 药物发现与设计中心 |
| 作者单位 | 1.Department of Life Sciences and Technology, Nantong Normal College, Nantong, Jiangsu 226007, China.; 2.Shanghai Institute of Materia Medica, Shanghai Institute for Biological Sceicnes, Chinese Academy of Sciences, Shanghai 200031, China. |
| 推荐引用方式 GB/T 7714 | Ye Hui,Yang Yushe,Xie Huansong,et al. Susceptibilities of Mycoplasma and ureaplasma to derivatives (YH16, YH17) of sparfloxacin in vitro[J]. Chinese Journal of Antibiotics,2003,28(8):494-496. |
| APA | Ye Hui,Yang Yushe,Xie Huansong,Wu Jimin,Chen Kaixian,&Ji Ruyuan.(2003).Susceptibilities of Mycoplasma and ureaplasma to derivatives (YH16, YH17) of sparfloxacin in vitro.Chinese Journal of Antibiotics,28(8),494-496. |
| MLA | Ye Hui,et al."Susceptibilities of Mycoplasma and ureaplasma to derivatives (YH16, YH17) of sparfloxacin in vitro".Chinese Journal of Antibiotics 28.8(2003):494-496. |
入库方式： OAI收割
来源：上海药物研究所
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