Cytotoxic lanostanoid triterpenes from Ganoderma lucidum
文献类型：期刊论文
| 作者 | Guan, Shu-Hong ; Xia, Jia-Meng; Yang, Min; Wang, Xiao-Ming; Liu, Xuan; Guo, De-An
|
| 刊名 | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
 |
| 出版日期 | 2008 |
| 卷号 | 10期号:8页码:695-700 |
| 关键词 | lanostanoid triterpenes Ganoderma lucidum fruit bodies cytotoxicity |
| ISSN号 | 1028-6020 |
| DOI | 10.1080/10286020802016297 |
| 文献子类 | Article |
| 英文摘要 | Two new lanostanoid triterpenes, 23S-hydroxy-3,7,11,15-tetraoxo-lanost-8,24E-diene-26-oic acid (1), and 12 beta-acetoxy-3 beta-hydroxy-7,11,15,23-tetraoxo-lanost-8,20E-diene-26-oic acid (16), together with 17 known compounds, were isolated from the fruit bodies of Ganoderma lucidum. Their structures were established by spectroscopic methods, especially 2D-NMR and MS analyses and by comparison with literature data. The cytotoxic assay of the above compounds against p388, Hela, BEL-7402, and SGC-7901 human cancer cell lines showed their cytotoxicity with the IC(50) values in the range of 8-25 mu m. |
| WOS关键词 | INHIBITORY TRITERPENES ; FR KARST ; ACID-D ; TERPENOIDS ; MICE ; POLYSACCHARIDES ; CONSTITUENTS ; CELLS |
| WOS研究方向 | Plant Sciences ; Chemistry ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000258321500001 |
| 出版者 | TAYLOR & FRANCIS LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273058]  |
| 专题 | 上海中药现代化研究中心 成果转移转化处 |
| 通讯作者 | Guo, De-An |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai Inst Biol Sci, Shanghai Res Ctr TCM Modernizat, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Guan, Shu-Hong,Xia, Jia-Meng,Yang, Min,et al. Cytotoxic lanostanoid triterpenes from Ganoderma lucidum[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2008,10(8):695-700. |
| APA | Guan, Shu-Hong,Xia, Jia-Meng,Yang, Min,Wang, Xiao-Ming,Liu, Xuan,&Guo, De-An.(2008).Cytotoxic lanostanoid triterpenes from Ganoderma lucidum.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,10(8),695-700. |
| MLA | Guan, Shu-Hong,et al."Cytotoxic lanostanoid triterpenes from Ganoderma lucidum".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 10.8(2008):695-700. |
入库方式： OAI收割
来源：上海药物研究所
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