Two new lanostanoid Triterpenes from the fruit body of ganoderma lucidum-the major component of SunRecome (R)
文献类型：期刊论文
| 作者 | Guan, Shu-Hong ; Yang, Min; Liu, Xuan; Xia, Jia-Meng; Wang, Xiao-Ming; Jin, Hui; Guo, De-an
|
| 刊名 | NATURAL PRODUCT COMMUNICATIONS
 |
| 出版日期 | 2006 |
| 卷号 | 1期号:3页码:177-181 |
| 关键词 | cytotoxic lanostanoid triterpenes Ganoderma lucidum SunRecome (R) |
| ISSN号 | 1934-578X |
| 文献子类 | Article |
| 英文摘要 | Two new lanostanoid triterpenes named 3 beta-hydroxy-4,4,14-trimethyl-7,11,15-trioxochol-8-en-24-oic acid (1) and 3 beta-Ahydroxy-7,11,12,15,23-pentaoxo-lanost-8-en-26-oic acid (2) were isolated from the fruit bodies of Ganoderma lucidum, which is the major component of the antitumor product SunRecome((R)). Their cytotoxic activities were assayed in vitro against HeLa, p388, SGC-7901, BEL-7402 cell lines, and the results showed that 1 had IC50 values of 18.00 mu M against p388 cell, 12.70 mu M against Hela cell, 22.00 mu M against BEL-7402 cell, 1.50 mu M against SGC-7901 cell and 2 had IC50 values of 9.85 mu M against p388 cell, 17.10 mu M against Hela cell, 51.00 mu M against BEL-7402 cell, 42.00 mu M against SGC-7901 cell. |
| WOS关键词 | TUMOR-CELLS ; CYTOTOXICITY ; SPORES ; APOPTOSIS ; ACID |
| WOS研究方向 | Pharmacology & Pharmacy ; Food Science & Technology |
| 语种 | 英语 |
| WOS记录号 | WOS:000249005900001 |
| 出版者 | NATURAL PRODUCTS INC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273746]  |
| 专题 | 上海中药现代化研究中心 成果转移转化处 |
| 通讯作者 | Guo, De-an |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Biolog Sci, Shanghai Inst Mat Med, Shanghai Res Ctr Modernizat Tradit Chinese Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Guan, Shu-Hong,Yang, Min,Liu, Xuan,et al. Two new lanostanoid Triterpenes from the fruit body of ganoderma lucidum-the major component of SunRecome (R)[J]. NATURAL PRODUCT COMMUNICATIONS,2006,1(3):177-181. |
| APA | Guan, Shu-Hong.,Yang, Min.,Liu, Xuan.,Xia, Jia-Meng.,Wang, Xiao-Ming.,...&Guo, De-an.(2006).Two new lanostanoid Triterpenes from the fruit body of ganoderma lucidum-the major component of SunRecome (R).NATURAL PRODUCT COMMUNICATIONS,1(3),177-181. |
| MLA | Guan, Shu-Hong,et al."Two new lanostanoid Triterpenes from the fruit body of ganoderma lucidum-the major component of SunRecome (R)".NATURAL PRODUCT COMMUNICATIONS 1.3(2006):177-181. |
入库方式： OAI收割
来源：上海药物研究所
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