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Phenanthrenes, 9,10-dihydrophenanthrenes, bibenzyls with their derivatives, and malate or tartrate benzyl ester glucosides from tubers of Cremastra appendiculata

文献类型：期刊论文

作者Wang, Yang1,2; Guan, Shu-Hong1; Meng, Yu-Hui1; Zhang, Yi-Bei1; Cheng, Chun-Ru1; Shi, Yang-Yang1; Feng, Rui-Hong1; Zeng, Feng1; Wu, Zhi-Yuan1; Zhang, Jing-Xian1,2
刊名PHYTOCHEMISTRY
出版日期2013-10
卷号94页码:268-276
关键词Cremastra appendiculata Orchidaceae Bibenzyl Phenanthrene 9,10-Dihydrophenanthrene 2,3,4,5-Tetrahydro-phenanthro[2,1-b]furan Malate benzyl ester glucoside Tartrate benzyl ester glucoside
ISSN号0031-9422
DOI10.1016/j.phytochem.2013.06.001
文献子类Article
英文摘要Eleven previously unknown compounds and 23 known compounds, including 20 phenanthrene or 9,10-dihydrophenanthrene derivatives, five bibenzyls, seven malate or tartrate benzyl ester glucosides, adenosine and gastrodin were isolated from tubers of Cremastra appendiculata. Among the obtained compounds, two are the first isolated dimers with one phenanthrene or bibenzyl unit connected to C-3 of 2,3,4,5-tetrahydro-phenanthro[2,1-b]furan moiety. In addition, 33 of these compounds were evaluated in vitro for their cytotoxic activity against two cancer cell lines. Among the compounds examined, one compound showed moderate cytotoxic activity, while five showed weak cytotoxic activity against the A549 cell line. (C) 2013 Elsevier Ltd. All rights reserved.
WOS关键词BLETILLA-STRIATA ; CHEMICAL-CONSTITUENTS ; GYMNADENIA-CONOPSEA ; STILBENOIDS ; DIHYDROPHENANTHRENES ; HOMOISOFLAVANONE ; BIPHENANTHRENES ; ORCHIDACEAE ; ORCHINOL
资助项目Twelfth Five-Year National Science & Technology Support Program[2012BAI29B06] ; Major Projects of Knowledge Innovation Program of the Chinese Academy of Sciences[KSCX2-YW-R-166] ; National Science & Technology Major Project "Key New Drug Creation and Manufacturing Program", China[2011ZX09307-002-03]
WOS研究方向Biochemistry & Molecular Biology ; Plant Sciences
语种英语
WOS记录号WOS:000324721100032
出版者PERGAMON-ELSEVIER SCIENCE LTD
源URL[http://119.78.100.183/handle/2S10ELR8/277445]  
专题成果转移转化处
通讯作者Guan, Shu-Hong
作者单位1.Chinese Acad Sci, Shanghai Res Ctr Modernizat Tradit Chinese Med, Natl Engn Lab TCM Standardizat Technol, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China;
2.Shenyang Pharmaceut Univ, Sch Pharm, Shenyang 110016, Liaoning Provin, Peoples R China
推荐引用方式
GB/T 7714		 Wang, Yang,Guan, Shu-Hong,Meng, Yu-Hui,et al. Phenanthrenes, 9,10-dihydrophenanthrenes, bibenzyls with their derivatives, and malate or tartrate benzyl ester glucosides from tubers of Cremastra appendiculata[J]. PHYTOCHEMISTRY,2013,94:268-276.
APA Wang, Yang.,Guan, Shu-Hong.,Meng, Yu-Hui.,Zhang, Yi-Bei.,Cheng, Chun-Ru.,...&Guo, De-An.(2013).Phenanthrenes, 9,10-dihydrophenanthrenes, bibenzyls with their derivatives, and malate or tartrate benzyl ester glucosides from tubers of Cremastra appendiculata.PHYTOCHEMISTRY,94,268-276.
MLA Wang, Yang,et al."Phenanthrenes, 9,10-dihydrophenanthrenes, bibenzyls with their derivatives, and malate or tartrate benzyl ester glucosides from tubers of Cremastra appendiculata".PHYTOCHEMISTRY 94(2013):268-276.

入库方式： OAI收割

来源：上海药物研究所

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