中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Cytotoxic triterpenoids from Ganoderma lucidum

文献类型:期刊论文

作者Cheng, Chun-Ru; Yue, Qing-Xi; Wu, Zhi-Yuan; Song, Xiao-Yi; Tao, Si-Jia; Wu, Xiao-Hui; Xu, Ping-Ping; Liu, Xuan; Guan, Shu-Hong; Guo, De-An
刊名PHYTOCHEMISTRY
出版日期2010-09
卷号71期号:13页码:1579-1585
关键词Ganoderma lucidum Triterpenoids Cytotoxicity Structure and activity relationship
ISSN号0031-9422
DOI10.1016/j.phytochem.2010.06.005
文献子类Article
英文摘要A systematic study of the metabolites in Ganoderma lucidum led to isolation of 43 triterpenoids, six of them (1-6) are hitherto unknown. The structures of the latter were elucidated on the basis of spectroscopic studies and comparison with the known related compounds. All of the compounds were assayed for their inhibitory activities against human HeLa cervical cancer cell lines. Some compounds exhibit significant cytotoxicity, and their structure-activity relationships are discussed. (C) 2010 Elsevier Ltd. All rights reserved.
WOS关键词TUMOR-CELL-LINES ; FR KARST ; ACID-F ; INHIBITORY TRITERPENES ; GANOLUCIDIC ACID ; CONSTITUENTS ; LANOSTANOIDS ; TERPENOIDS ; METABOLITES ; BITTERNESS
资助项目National Natural Science Foundation of China (NNSFC)[30701077] ; ministry of Sciences and Technology of China[2006BAI08B03-03] ; National Science and Technology Major Project "Key New Drug Creation and Manufacturing Program", China[2009ZX09308-005] ; National Science and Technology Major Project "Key New Drug Creation and Manufacturing Program", China[2009ZX09311-001] ; National Science and Technology Major Project "Key New Drug Creation and Manufacturing Program", China[2009ZX09502-020] ; Ministry of Science and Technology of the People's Republic of China[00000000]
WOS研究方向Biochemistry & Molecular Biology ; Plant Sciences
语种英语
WOS记录号WOS:000280983200018
出版者PERGAMON-ELSEVIER SCIENCE LTD
源URL[http://119.78.100.183/handle/2S10ELR8/278793]  
专题成果转移转化处
上海中药现代化研究中心
通讯作者Guan, Shu-Hong
作者单位Chinese Acad Sci, Shanghai Res Ctr Modernizat Tradit Chinese Med, Natl Engn Lab TCM Standardizat Technol, Shanghai Inst Mat Med,Shanghai Inst Biol Sci, Shanghai 201203, Peoples R China
推荐引用方式
GB/T 7714
Cheng, Chun-Ru,Yue, Qing-Xi,Wu, Zhi-Yuan,et al. Cytotoxic triterpenoids from Ganoderma lucidum[J]. PHYTOCHEMISTRY,2010,71(13):1579-1585.
APA Cheng, Chun-Ru.,Yue, Qing-Xi.,Wu, Zhi-Yuan.,Song, Xiao-Yi.,Tao, Si-Jia.,...&Guo, De-An.(2010).Cytotoxic triterpenoids from Ganoderma lucidum.PHYTOCHEMISTRY,71(13),1579-1585.
MLA Cheng, Chun-Ru,et al."Cytotoxic triterpenoids from Ganoderma lucidum".PHYTOCHEMISTRY 71.13(2010):1579-1585.

入库方式: OAI收割

来源:上海药物研究所

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