Cytotoxic triterpenoids from Ganoderma lucidum
文献类型:期刊论文
作者 | Cheng, Chun-Ru; Yue, Qing-Xi; Wu, Zhi-Yuan; Song, Xiao-Yi; Tao, Si-Jia; Wu, Xiao-Hui; Xu, Ping-Ping; Liu, Xuan; Guan, Shu-Hong![]() ![]() |
刊名 | PHYTOCHEMISTRY
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出版日期 | 2010-09 |
卷号 | 71期号:13页码:1579-1585 |
关键词 | Ganoderma lucidum Triterpenoids Cytotoxicity Structure and activity relationship |
ISSN号 | 0031-9422 |
DOI | 10.1016/j.phytochem.2010.06.005 |
文献子类 | Article |
英文摘要 | A systematic study of the metabolites in Ganoderma lucidum led to isolation of 43 triterpenoids, six of them (1-6) are hitherto unknown. The structures of the latter were elucidated on the basis of spectroscopic studies and comparison with the known related compounds. All of the compounds were assayed for their inhibitory activities against human HeLa cervical cancer cell lines. Some compounds exhibit significant cytotoxicity, and their structure-activity relationships are discussed. (C) 2010 Elsevier Ltd. All rights reserved. |
WOS关键词 | TUMOR-CELL-LINES ; FR KARST ; ACID-F ; INHIBITORY TRITERPENES ; GANOLUCIDIC ACID ; CONSTITUENTS ; LANOSTANOIDS ; TERPENOIDS ; METABOLITES ; BITTERNESS |
资助项目 | National Natural Science Foundation of China (NNSFC)[30701077] ; ministry of Sciences and Technology of China[2006BAI08B03-03] ; National Science and Technology Major Project "Key New Drug Creation and Manufacturing Program", China[2009ZX09308-005] ; National Science and Technology Major Project "Key New Drug Creation and Manufacturing Program", China[2009ZX09311-001] ; National Science and Technology Major Project "Key New Drug Creation and Manufacturing Program", China[2009ZX09502-020] ; Ministry of Science and Technology of the People's Republic of China[00000000] |
WOS研究方向 | Biochemistry & Molecular Biology ; Plant Sciences |
语种 | 英语 |
WOS记录号 | WOS:000280983200018 |
出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
源URL | [http://119.78.100.183/handle/2S10ELR8/278793] ![]() |
专题 | 成果转移转化处 上海中药现代化研究中心 |
通讯作者 | Guan, Shu-Hong |
作者单位 | Chinese Acad Sci, Shanghai Res Ctr Modernizat Tradit Chinese Med, Natl Engn Lab TCM Standardizat Technol, Shanghai Inst Mat Med,Shanghai Inst Biol Sci, Shanghai 201203, Peoples R China |
推荐引用方式 GB/T 7714 | Cheng, Chun-Ru,Yue, Qing-Xi,Wu, Zhi-Yuan,et al. Cytotoxic triterpenoids from Ganoderma lucidum[J]. PHYTOCHEMISTRY,2010,71(13):1579-1585. |
APA | Cheng, Chun-Ru.,Yue, Qing-Xi.,Wu, Zhi-Yuan.,Song, Xiao-Yi.,Tao, Si-Jia.,...&Guo, De-An.(2010).Cytotoxic triterpenoids from Ganoderma lucidum.PHYTOCHEMISTRY,71(13),1579-1585. |
MLA | Cheng, Chun-Ru,et al."Cytotoxic triterpenoids from Ganoderma lucidum".PHYTOCHEMISTRY 71.13(2010):1579-1585. |
入库方式: OAI收割
来源:上海药物研究所
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