Research Progress in HIV Integrase Inhibitors
文献类型：期刊论文
| 作者 | Guo Diliang1,2; Liu Guannan1; Zhou Yu1 ; Li Jian1; Xu Jinyi2; Jiang Hualiang1; Chen Kaixian1; Liu Hong1,2
|
| 刊名 | CHINESE JOURNAL OF ORGANIC CHEMISTRY
 |
| 出版日期 | 2010-04 |
| 卷号 | 30期号:4页码:477-485 |
| 关键词 | HIV integrase inhibitor diketoacid Raltegrayir |
| ISSN号 | 0253-2786 |
| 文献子类 | Article |
| 英文摘要 | HIV integrase is one of the three essential enzymes for viral DNA replication and the molecular target of the newly approved anti-AIDS drug raltegravir (MK-0518, Isentress). HIV integrase inhibitors have emerged as a new class of drugs for the treatment of AIDS. In this article, the recent progress of HIV integrase inhibitors is reviewed to provide some useful information for the further research and development of HIV integrase inhibitors. |
| WOS关键词 | IMMUNODEFICIENCY-VIRUS INTEGRASE ; RALTEGRAVIR MK-0518 ; IN-VITRO ; DESIGN ; POTENT ; CHEMOTHERAPY ; FLAVONES ; MUTANTS ; THERAPY ; UPDATE |
| WOS研究方向 | Chemistry |
| 语种 | 中文 |
| CSCD记录号 | CSCD:3939592 |
| WOS记录号 | WOS:000277485200001 |
| 出版者 | SCIENCE CHINA PRESS |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/278928]  |
| 专题 | 药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 药物发现与设计中心 |
| 通讯作者 | Guo Diliang |
| 作者单位 | 1.Chinese Acad Sci, Drug Discovery & Design Ctr, State Key Lab Drug Res, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China; 2.China Pharmaceut Univ, Sch Pharm, Nanjing 210009, Peoples R China |
| 推荐引用方式 GB/T 7714 | Guo Diliang,Liu Guannan,Zhou Yu,et al. Research Progress in HIV Integrase Inhibitors[J]. CHINESE JOURNAL OF ORGANIC CHEMISTRY,2010,30(4):477-485. |
| APA | Guo Diliang.,Liu Guannan.,Zhou Yu.,Li Jian.,Xu Jinyi.,...&Liu Hong.(2010).Research Progress in HIV Integrase Inhibitors.CHINESE JOURNAL OF ORGANIC CHEMISTRY,30(4),477-485. |
| MLA | Guo Diliang,et al."Research Progress in HIV Integrase Inhibitors".CHINESE JOURNAL OF ORGANIC CHEMISTRY 30.4(2010):477-485. |
入库方式： OAI收割
来源：上海药物研究所
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