Rare Casbane Diterpenoids from the Hainan Soft Coral Sinularia depressa
文献类型：期刊论文
| 作者 | Li, Yan2; Carbone, Marianna1; Vitale, Rosa Maria1; Amodeo, Pietro1; Castelluccio, Francesco1; Sicilia, Giovanna1; Mollo, Ernesto1; Nappo, Michela1; Cimino, Guido1; Guo, Yue-Wei2
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| 刊名 | JOURNAL OF NATURAL PRODUCTS
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| 出版日期 | 2010-02 |
| 卷号 | 73期号:2页码:133-138 |
| ISSN号 | 0163-3864 |
| DOI | 10.1021/np900484k |
| 文献子类 | Article |
| 英文摘要 | A series of nine casbane diterpenes, compounds 5-13. exhibiting either cis or trans ring junctions were isolated from the Hainan soft coral Sinularia depressa. The structures of this group of compounds, the basic member of which was named depressin (5), were established by detailed spectroscopic analysis. In addition, the absolute configuration of the main metabolite, 10-hydroxydepressin (7), and of its epimer, 1-epi-10-hydroxydepressin (8). was determined by it combination of conformational analysis and the modified Mosher's method. A stereochemical relationship between all isolated molecules was investigated by analyzing then circular dichroism profiles. Antiproliferative and antibacterial activities of the depressins were also evaluated. |
| WOS关键词 | SARCOPHYTON-LATUM ; FORCE-FIELD ; IDENTIFICATION ; TERPENOIDS ; CHEMISTRY ; MODEL |
| 资助项目 | national S & T major project[20092X09301-001] ; national marine 863 project[2007AA09Z447] ; NSFC[40976048] ; NSFC[30730108] ; NSFC[20721003] ; CAS[KSX2-YW-R-18] ; CAS[SIMM0907KF-09] ; PRIN-MIUR[00000000] |
| WOS研究方向 | Plant Sciences ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| 出版者 | AMER CHEMICAL SOC |
| WOS记录号 | WOS:000274803600008 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/278984]  |
| 专题 | 天然药物化学研究室 中科院受体结构与功能重点实验室 信息中心 新药研究国家重点实验室 药理学第一研究室 |
| 通讯作者 | Guo, Yue-Wei |
| 作者单位 | 1.CNR, ICB, I-80078 Naples, Italy 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Li, Yan,Carbone, Marianna,Vitale, Rosa Maria,et al. Rare Casbane Diterpenoids from the Hainan Soft Coral Sinularia depressa[J]. JOURNAL OF NATURAL PRODUCTS,2010,73(2):133-138. |
| APA | Li, Yan.,Carbone, Marianna.,Vitale, Rosa Maria.,Amodeo, Pietro.,Castelluccio, Francesco.,...&Gavagnin, Margherita.(2010).Rare Casbane Diterpenoids from the Hainan Soft Coral Sinularia depressa.JOURNAL OF NATURAL PRODUCTS,73(2),133-138. |
| MLA | Li, Yan,et al."Rare Casbane Diterpenoids from the Hainan Soft Coral Sinularia depressa".JOURNAL OF NATURAL PRODUCTS 73.2(2010):133-138. |
入库方式： OAI收割
来源：上海药物研究所
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