Stereoselective Synthesis of Methyl Spongoate, a New Steroid with Potent Antitumor Activities
文献类型：期刊论文
| 作者 | Gong, Jing-Xu2; Miao, Ze-Hong2; Yao, Li-Gong2; Ding, Jian2 ; Kurtan, Tibor1; Guo, Yue-Wei2
|
| 刊名 | SYNLETT
 |
| 出版日期 | 2010-02 |
| 期号 | 3页码:480-482 |
| 关键词 | steroids methyl spongoate stereoselective synthesis diastereoselective alkylation cytotoxicity |
| ISSN号 | 0936-5214 |
| DOI | 10.1055/s-0029-1218567 |
| 文献子类 | Article |
| 英文摘要 | The stereoselective synthesis of methyl spongoate, a naturally occurring new steroid derivative with an unusual C-20 methoxycarbonyl group and potent antitumor activities, was achieved starting from the commercially available pregnenolone acetate in 11% overall yield. |
| WOS关键词 | LISSOCLINOTOXIN-A ; DERIVATIVES ; VARACIN |
| 资助项目 | National Marine '863' Project[2006AA09Z447] ; National Marine '863' Project[2006AA09Z412] ; CAS Key Project[SIMM0907KF-09] ; Hungarian-Chinese Intergovermental S&T Cooperation Programme[00000000] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000274233900029 |
| 出版者 | GEORG THIEME VERLAG KG |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/278988]  |
| 专题 | 天然药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Guo, Yue-Wei |
| 作者单位 | 1.Univ Debrecen, Dept Organ Chem, H-4010 Debrecen, Hungary 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Gong, Jing-Xu,Miao, Ze-Hong,Yao, Li-Gong,et al. Stereoselective Synthesis of Methyl Spongoate, a New Steroid with Potent Antitumor Activities[J]. SYNLETT,2010(3):480-482. |
| APA | Gong, Jing-Xu,Miao, Ze-Hong,Yao, Li-Gong,Ding, Jian,Kurtan, Tibor,&Guo, Yue-Wei.(2010).Stereoselective Synthesis of Methyl Spongoate, a New Steroid with Potent Antitumor Activities.SYNLETT(3),480-482. |
| MLA | Gong, Jing-Xu,et al."Stereoselective Synthesis of Methyl Spongoate, a New Steroid with Potent Antitumor Activities".SYNLETT .3(2010):480-482. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。