SYNTHESIS OF 4-AZACHROMENO[2,3-b]INDOL-11(6H)-ONE AND ITS DERIVATIVES AS ANALOGUES OF ELLIPTICINE
文献类型：期刊论文
| 作者 | Chen, Yanhong; Yang, Chunhao ; Xie, Yuyuan
|
| 刊名 | HETEROCYCLES
 |
| 出版日期 | 2010 |
| 卷号 | 80期号:1页码:251-258 |
| 关键词 | Azachromeno[2,3-b]indol-11(6H)-one Ellipticine Indolin-2-one Antitumor Cyclization |
| ISSN号 | 0385-5414 |
| DOI | 10.3987/COM-08-S(S)3 |
| 文献子类 | Article |
| 英文摘要 | 4-Azachromeno[2,3-b]indol-11(6H)-ones (4) and their derivatives (5) as analogues of ellipticine were synthesized through a straightforward, two or three-step process. Tetracyclic heterocycles (4) were obtained by facile cyclization of indolin-2-ones (2) or (3) and 2-chloronicotinoyl chloride under the condition of the 'Jensen'-reaction. Alkylation of the compounds (4) afforded 6-substituted 4-azachromeno[2,3-b]indol-11(6H)-ones. |
| WOS关键词 | ALKALOIDS ; PYRIDINES |
| 资助项目 | Chinese Academy of Sciences[KSCX2-YW-R-25] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000287635800025 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/279031]  |
| 专题 | 药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Chen, Yanhong |
| 作者单位 | Chinese Acad Sci, SIBS, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Yanhong,Yang, Chunhao,Xie, Yuyuan. SYNTHESIS OF 4-AZACHROMENO[2,3-b]INDOL-11(6H)-ONE AND ITS DERIVATIVES AS ANALOGUES OF ELLIPTICINE[J]. HETEROCYCLES,2010,80(1):251-258. |
| APA | Chen, Yanhong,Yang, Chunhao,&Xie, Yuyuan.(2010).SYNTHESIS OF 4-AZACHROMENO[2,3-b]INDOL-11(6H)-ONE AND ITS DERIVATIVES AS ANALOGUES OF ELLIPTICINE.HETEROCYCLES,80(1),251-258. |
| MLA | Chen, Yanhong,et al."SYNTHESIS OF 4-AZACHROMENO[2,3-b]INDOL-11(6H)-ONE AND ITS DERIVATIVES AS ANALOGUES OF ELLIPTICINE".HETEROCYCLES 80.1(2010):251-258. |
入库方式： OAI收割
来源：上海药物研究所
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