Silver-Catalyzed Intramolecular Cyclization of o-(1-Alkynyl)benzamides: Efficient Synthesis of (1H)-Isochromen-1-imines
文献类型：期刊论文
| 作者 | Liu, Guannan1; Zhou, Yu1 ; Ye, Deju1; Zhang, Dengyou1; Ding, Xiao1; Jiang, Hualiang1,2; Liu, Hong1
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| 刊名 | ADVANCED SYNTHESIS & CATALYSIS
 |
| 出版日期 | 2009-11 |
| 卷号 | 351期号:16页码:2605-2610 |
| 关键词 | intramolecular cyclization (1H)-isochromen-1-imines organic catalysis regioselectivity silver catalyst synthetic methods |
| ISSN号 | 1615-4150 |
| DOI | 10.1002/adsc.200900381 |
| 文献子类 | Article |
| 英文摘要 | An efficient avenue for the facile and atom-economic synthesis of (1H)-isochromen-1-imines has been developed, and a broad spectrum of substrates can participate in the process effectively to produce the desired products in good yields. Significantly, this is the first report of the synthesis of (1H)-isochromen-1-imines that involves a silver(I)-catalyzed, regiocontrolled intramolecular addition of the carbonyl group of the amide moiety towards an alkyne. |
| WOS关键词 | MULTIPLE-MYELOMA ; ALKYNES ; ISOQUINOLINES ; HYDROAMINATION ; ISOCOUMARINS ; DERIVATIVES ; ROUTE ; BONDS ; ACIDS |
| 资助项目 | National Natural Science Foundation of China[20721003] ; National Natural Science Foundation of China[20872153] ; International Collaboration[2007DFB30370] ; International Collaboration[20720102040] ; 863 Hi-Tech Program of China[2006AA020602] ; 863 Hi-Tech Program of China[2006AA10A201] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000272252900013 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/279086]  |
| 专题 | 药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Liu, Hong |
| 作者单位 | 1.Chinese Acad Sci, Drug Discovery & Design Ctr, State Key Lab Drug Res, Shanghai Inst Mat Med,Shanghai Inst Biol Sci, Shanghai 201203, Peoples R China; 2.E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Guannan,Zhou, Yu,Ye, Deju,et al. Silver-Catalyzed Intramolecular Cyclization of o-(1-Alkynyl)benzamides: Efficient Synthesis of (1H)-Isochromen-1-imines[J]. ADVANCED SYNTHESIS & CATALYSIS,2009,351(16):2605-2610. |
| APA | Liu, Guannan.,Zhou, Yu.,Ye, Deju.,Zhang, Dengyou.,Ding, Xiao.,...&Liu, Hong.(2009).Silver-Catalyzed Intramolecular Cyclization of o-(1-Alkynyl)benzamides: Efficient Synthesis of (1H)-Isochromen-1-imines.ADVANCED SYNTHESIS & CATALYSIS,351(16),2605-2610. |
| MLA | Liu, Guannan,et al."Silver-Catalyzed Intramolecular Cyclization of o-(1-Alkynyl)benzamides: Efficient Synthesis of (1H)-Isochromen-1-imines".ADVANCED SYNTHESIS & CATALYSIS 351.16(2009):2605-2610. |
入库方式： OAI收割
来源：上海药物研究所
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