中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 上海药物研究所
  3. 中国科学院上海药物研究所
  4. 药物化学研究室
A New Approach to Pyrrolocoumarin Derivatives by Palladium-Catalyzed Reactions: Expedient Construction of Polycyclic Lamellarin Scaffold

文献类型：期刊论文

作者Chen, Lei; Xu, Ming-Hua
刊名ADVANCED SYNTHESIS & CATALYSIS
出版日期2009-08
卷号351期号:11-12页码:2005-2012
关键词coumarin derivatives cross-coupling hydroamination lamellarin palladium
ISSN号1615-4150
DOI10.1002/adsc.200900287
文献子类Article
英文摘要A new and efficient protocol for straightforward synthesis of chromeno[3,4-b]pyrrol-4(3H)-one derivatives by palladium-catalyzed sequential coupling/cyclization reactions has been developed. The key strategy relies on creation of pyrrole ring through palladium-catalyzed intramolecular hydroamination of related acetylenic aminocoumarins. The synthetic utility of the obtained chromeno[3,4-b]pyrrol-4(3H)-one product has been demonstrated by the expedient synthesis of polycyclic lamellarin scaffold in four steps. It provides a new entry to synthesis of potentially valuable lamellarin analogues.
WOS关键词RESISTANCE REVERSAL ACTIVITY ; CROSS-COUPLING REACTIONS ; G TRIMETHYL ETHER ; 4-SUBSTITUTED COUMARINS ; NINGALIN-B ; PERMETHYL STORNIAMIDE ; ORGANOZINC REAGENTS ; ARYLBORONIC ACIDS ; ALPHA 20-SULFATE ; ANALOGS
资助项目National Natural Science Foundation of China[20721003] ; Shanghai Rising-Star Program[08QH14027] ; Chinese Academy of Sciences[00000000] ; Shanghai Institute of Materia Medica[00000000]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000269583900042
出版者WILEY-V C H VERLAG GMBH
源URL[http://119.78.100.183/handle/2S10ELR8/279165]  
专题药物化学研究室
中科院受体结构与功能重点实验室
新药研究国家重点实验室
通讯作者Xu, Ming-Hua
作者单位Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China
推荐引用方式
GB/T 7714		 Chen, Lei,Xu, Ming-Hua. A New Approach to Pyrrolocoumarin Derivatives by Palladium-Catalyzed Reactions: Expedient Construction of Polycyclic Lamellarin Scaffold[J]. ADVANCED SYNTHESIS & CATALYSIS,2009,351(11-12):2005-2012.
APA Chen, Lei,&Xu, Ming-Hua.(2009).A New Approach to Pyrrolocoumarin Derivatives by Palladium-Catalyzed Reactions: Expedient Construction of Polycyclic Lamellarin Scaffold.ADVANCED SYNTHESIS & CATALYSIS,351(11-12),2005-2012.
MLA Chen, Lei,et al."A New Approach to Pyrrolocoumarin Derivatives by Palladium-Catalyzed Reactions: Expedient Construction of Polycyclic Lamellarin Scaffold".ADVANCED SYNTHESIS & CATALYSIS 351.11-12(2009):2005-2012.

入库方式： OAI收割

来源：上海药物研究所

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。