Facile Synthesis of 1,2,3,4-Tetrahydrobenzo[b][1,8]naphthyridin-2-one via Baylis-Hillman Adducts
文献类型：期刊论文
| 作者 | Chen Dongdong; Xu jing; Yang Chunhao ; Xie Yuyuan
|
| 刊名 | CHINESE JOURNAL OF CHEMISTRY
 |
| 出版日期 | 2009-04 |
| 卷号 | 27期号:4页码:787-790 |
| 关键词 | benzo[b][1,8]naphthyridin-2-one Baylis-Hillman reaction Johnson-Claisen rearrangement reduction double cyclization |
| ISSN号 | 1001-604X |
| DOI | 10.1002/cjoc.200990131 |
| 文献子类 | Article |
| 英文摘要 | Various benzo[b][1,8]naphthyridin-2-ones were synthesized by a one-pot tandem reduction-double cyclization from the corresponding (7-)-ethyl 4-cyano-5-(2-nitrophenyl)-pent-4-enoates, which were easily prepared via Johnson-Claisen rearrangement from Baylis-Hillman affixtures of 2-nitrobenzaldehydes. The procedure has the advantages of easy handling and seperation under mild and green conditions, and the overall yields are moderate. |
| WOS关键词 | AZA ANALOGS ; BEHAVIOR |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| CSCD记录号 | CSCD:3630676 |
| WOS记录号 | WOS:000265717900031 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/279274]  |
| 专题 | 药物化学研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Yang Chunhao |
| 作者单位 | Chinese Acad Sci, State Key Lab Drug Res, Shanghai Inst Mat Med, SIBS, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen Dongdong,Xu jing,Yang Chunhao,et al. Facile Synthesis of 1,2,3,4-Tetrahydrobenzo[b][1,8]naphthyridin-2-one via Baylis-Hillman Adducts[J]. CHINESE JOURNAL OF CHEMISTRY,2009,27(4):787-790. |
| APA | Chen Dongdong,Xu jing,Yang Chunhao,&Xie Yuyuan.(2009).Facile Synthesis of 1,2,3,4-Tetrahydrobenzo[b][1,8]naphthyridin-2-one via Baylis-Hillman Adducts.CHINESE JOURNAL OF CHEMISTRY,27(4),787-790. |
| MLA | Chen Dongdong,et al."Facile Synthesis of 1,2,3,4-Tetrahydrobenzo[b][1,8]naphthyridin-2-one via Baylis-Hillman Adducts".CHINESE JOURNAL OF CHEMISTRY 27.4(2009):787-790. |
入库方式： OAI收割
来源：上海药物研究所
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