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Diterpenoids from the Hainan Soft Coral Sinularia parva

文献类型：期刊论文

作者Li, Yan1; Gao, An-Hui1; Huang, Hui2; Li, Jia1; Mollo, Ernesto3; Gavagnin, Margherita3; Cimino, Guido3; Gu, Yu-Cheng4; Guo, Yue-Wei1
刊名HELVETICA CHIMICA ACTA
出版日期2009
卷号92期号:7页码:1341-1348
ISSN号0018-019X
DOI10.1002/hlca.200800447
文献子类Article
英文摘要Two new cembrane diterpenes, sinulaparvalides A and B (1 and 2, resp.), which contain an intriguing seven-membered lactone moiety, along with the four known related cembranoids 3-6, were isolated from the Hainan soft coral Sinularia parva. The structures of compounds I and 2 were established by spectroscopic methods, mainly on the basis of 2D-NMR techniques, and were confirmed by single-crystal X-ray diffraction analysis. The in vitro cytotoxic activities of these compounds were tested on human colon carcinoma (HCT-116), human promyelocytic leukemia (HL-60), and human lung carcinoma (A-549) tumor cell lines.
WOS关键词FLEXIBILIS ; CEMBRANOLIDE
资助项目National Marine 863 Projects[2006AA09Z447] ; National Marine 863 Projects[2006AA09Z412] ; National Marine 863 Projects[2007AA09Z402] ; Natural Science Foundation of China[30730108] ; Natural Science Foundation of China[20721003] ; Natural Science Foundation of China[20772136] ; STCSM Project[07XD14036] ; Syngenta-SIMM-PhD[00000000] ; CAS[KSCX2-YW-R-18]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000268622500013
出版者WILEY-V C H VERLAG GMBH
源URL[http://119.78.100.183/handle/2S10ELR8/279376]  
专题天然药物化学研究室
中科院受体结构与功能重点实验室
信息中心
新药研究国家重点实验室
药理学第一研究室
通讯作者Guo, Yue-Wei
作者单位1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China;
2.Chinese Acad Sci, S China Sea Inst Oceanol, Guangzhou 510301, Guangdong, Peoples R China;
3.CNR, Ist Chim Biomol, I-80078 Naples, Italy;
4.Syngenta, Jealotts Hill Int Res Ctr, Bracknell RG42 6EY, Berks, England
推荐引用方式
GB/T 7714		 Li, Yan,Gao, An-Hui,Huang, Hui,et al. Diterpenoids from the Hainan Soft Coral Sinularia parva[J]. HELVETICA CHIMICA ACTA,2009,92(7):1341-1348.
APA Li, Yan.,Gao, An-Hui.,Huang, Hui.,Li, Jia.,Mollo, Ernesto.,...&Guo, Yue-Wei.(2009).Diterpenoids from the Hainan Soft Coral Sinularia parva.HELVETICA CHIMICA ACTA,92(7),1341-1348.
MLA Li, Yan,et al."Diterpenoids from the Hainan Soft Coral Sinularia parva".HELVETICA CHIMICA ACTA 92.7(2009):1341-1348.

入库方式： OAI收割

来源：上海药物研究所

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