Heterocyclic Compounds from the Mushroom Albatrellus confluens and Their Inhibitions against Lipopolysaccharides-Induced B Lymphocyte Cell Proliferation
文献类型：期刊论文
| 作者 | Zhang, Shuaibing1,3,4; Huang, Ying1,3,4; He, Shijun2 ; Chen, Heping4; Wu, Bin4; Li, Shanyong1,3; Zhao, Zhenzhu1,3; Li, Zhenghui4; Wang, Xian4; Zuo, Jianping2
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| 刊名 | JOURNAL OF ORGANIC CHEMISTRY
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| 出版日期 | 2018-09-07 |
| 卷号 | 83期号:17页码:10158-10165 |
| ISSN号 | 0022-3263 |
| DOI | 10.1021/acs.joc.8b01420 |
| 文献子类 | Article |
| 英文摘要 | Eight hetereocyclic compounds conflamides B-I with an unprecedented skeleton and their precursor conflamide A were isolated from the mushroom Albatrellus confluens. Their structures and absolute configurations were determined by use of NMR studies, total synthesis, and calculated ECD spectra. Conflamides D and E were found to exhibit potent inhibition against LPS-induced B lymphocyte cell proliferation with IC50 values 1.48 and 5.71 mu M, respectively. |
| WOS关键词 | ALBACONOL ; SKELETONS ; CULTURES ; AMIDES ; ACIDS |
| 资助项目 | National Key Research and Development Program of China[2017YFC1704007] ; National Natural Science Foundation of China[81773590] ; National Natural Science Foundation of China[81561148013] ; Thailand Research Fund[DBGS980002] ; Key Projects of Technological Innovation of Hubei Province[2016ACA138] ; Fundamental Research Funds for the Central University[00000000] ; South-Central University for Nationalities[CZP18005] ; South-Central University for Nationalities[CZQ17010] ; South-Central University for Nationalities[CZQ17008] ; South-Central University for Nationalities[CZT18014] ; South-Central University for Nationalities[CZT18013] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000444364600049 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/279586]  |
| 专题 | 药理学第一研究室 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Zuo, Jianping; Feng, Tao; Liu, Jikai |
| 作者单位 | 1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China 3.Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China; 4.South Cent Univ Nationalities, Sch Pharmaceut Sci, Wuhan 430074, Hubei, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Zhang, Shuaibing,Huang, Ying,He, Shijun,et al. Heterocyclic Compounds from the Mushroom Albatrellus confluens and Their Inhibitions against Lipopolysaccharides-Induced B Lymphocyte Cell Proliferation[J]. JOURNAL OF ORGANIC CHEMISTRY,2018,83(17):10158-10165. |
| APA | Zhang, Shuaibing.,Huang, Ying.,He, Shijun.,Chen, Heping.,Wu, Bin.,...&Liu, Jikai.(2018).Heterocyclic Compounds from the Mushroom Albatrellus confluens and Their Inhibitions against Lipopolysaccharides-Induced B Lymphocyte Cell Proliferation.JOURNAL OF ORGANIC CHEMISTRY,83(17),10158-10165. |
| MLA | Zhang, Shuaibing,et al."Heterocyclic Compounds from the Mushroom Albatrellus confluens and Their Inhibitions against Lipopolysaccharides-Induced B Lymphocyte Cell Proliferation".JOURNAL OF ORGANIC CHEMISTRY 83.17(2018):10158-10165. |
入库方式： OAI收割
来源：上海药物研究所
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