Serratene-type triterpenoids from Palhinhaea cernua
文献类型：期刊论文
| 作者 | Wei, Jiao-Jiao1,2; Wang, Wen-Qiong1; Song, Wei-Bin1; Xuan, Li-Jiang1
|
| 刊名 | FITOTERAPIA
 |
| 出版日期 | 2018-06 |
| 卷号 | 127页码:151-158 |
| 关键词 | Palhinhaea cernua Serratene triterpenoids Apoptosis |
| ISSN号 | 0367-326X |
| DOI | 10.1016/j.fitote.2018.02.011 |
| 文献子类 | Article |
| 英文摘要 | Phytochemical investigation of the 95% ethanol extract of the whole plant of Palhinhaea cernua afforded five new serratene-type triterpenoids (1-5) together with four known analogues (6-9). The structures of the new compounds were elucidated by extensive spectroscopic analysis and X-ray crystallographic data. Compounds 1-3 triggered apoptosis of Hela(-/-) cell with EC50 values of 3.49 +/- 0.05, 0.28 +/- 0.13 and 7.98 +/- 0.03 mu M, respectively. |
| WOS关键词 | LYCOPODIUM-JAPONICUM ; XANTHINE-OXIDASE ; STEM BARK ; CHOLINESTERASE ; ALKALOIDS |
| 资助项目 | State Key Laboratory of Drug Research[SIMM1601ZZ-03] ; National Natural Science Foundation of China[81473111] |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000437551000023 |
| 出版者 | ELSEVIER SCIENCE BV |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/279718]  |
| 专题 | 上海中药现代化研究中心 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Xuan, Li-Jiang |
| 作者单位 | 1.Chinese Acad Sci, Inst Materia Med, State Key Lab Drug Res, 501 Haike Rd, Shanghai 201203, Peoples R China; 2.Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wei, Jiao-Jiao,Wang, Wen-Qiong,Song, Wei-Bin,et al. Serratene-type triterpenoids from Palhinhaea cernua[J]. FITOTERAPIA,2018,127:151-158. |
| APA | Wei, Jiao-Jiao,Wang, Wen-Qiong,Song, Wei-Bin,&Xuan, Li-Jiang.(2018).Serratene-type triterpenoids from Palhinhaea cernua.FITOTERAPIA,127,151-158. |
| MLA | Wei, Jiao-Jiao,et al."Serratene-type triterpenoids from Palhinhaea cernua".FITOTERAPIA 127(2018):151-158. |
入库方式： OAI收割
来源：上海药物研究所
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