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Sarinfacetamides A and B, Nitrogenous Diterpenoids with Tricyclo[6.3.1.0(1,5)]dodecane Scaffold from the South China Sea Soft Coral Sarcophyton infundibuliforme

文献类型：期刊论文

作者Ye, Fei1,2; Li, Jing3; Wu, Yu3; Zhu, Zheng-Dan1,2; Mollo, Ernesto5; Gavagnin, Margherita5; Gu, Yu-Cheng4; Zhu, Wei-Liang1,2,6; Li, Xu-Wen1,6; Guo, Yue-Wei1,2,6
刊名ORGANIC LETTERS
出版日期2018-05-04
卷号20期号:9页码:2637-2640
ISSN号1523-7060
DOI10.1021/acs.orglett.8b00842
文献子类Article
英文摘要Two novel nitrogenous diterpenoids, sarinfacetamides A (1) and B (2), featuring an uncommon tricydo[6.3.1.0(1,5)]dodecane scaffold, and a known related diterpene (3) were isolated from the South China Sea soft coral Sarcophyton infundibuliforme. Their structures, including the absolute configuration of 1, were established, by extensive spectroscopic analysis and TDDFT-ECD calculation. Compounds 1 and 3 exhibited interesting promotion effects on the ConA-induced T lymphocyte proliferation. A plausible biosynthetic pathway for 1 and 2 was also proposed.
WOS关键词SARCOPHYTON-TROCHELIOPHORUM MARENZELLER ; SESQUITERPENOIDS ; SKELETON
资助项目National Natural Science Foundation of China (NSFC)[81520108028] ; National Natural Science Foundation of China (NSFC)[21672230] ; National Natural Science Foundation of China (NSFC)[81603022] ; NSFC-Shandong Joint Fund for Marine Science Research Centers[U1606403] ; SKLDR/SIMM Project[SIMM1705ZZ-01] ; Syngenta-SIMM-PhD Studentship Project[00000000] ; "Youth Innovation Promotion Association" from Chinese Academy of Sciences[2016258] ; "Young Elite Scientists Sponsorship" from China Association for Science and Technology[2016QNRC001] ; Shanghai "Pujiang Program"[16PJ1410600] ; SA-SIBS Scholarship Program[00000000]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000431726900032
出版者AMER CHEMICAL SOC
源URL[http://119.78.100.183/handle/2S10ELR8/279766]  
专题天然药物化学研究室
中科院受体结构与功能重点实验室
新药研究国家重点实验室
通讯作者Li, Xu-Wen; Guo, Yue-Wei
作者单位1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zu Chong Zhi Rd,Zhangjiang Hitech Pk, Shanghai 201203, Peoples R China;
2.Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China;
3.Ocean Univ China, Sch Med & Pharm, Minist Educ, Key Lab Marine Drugs, 5 Yu Shan Rd, Qingdao 266003, Peoples R China;
4.Syngenta, Jealotts Hill Int Res Ctr, Bracknell RG42 6EY, Berks, England;
5.CNR, Natl Res Council, Inst Biomol Chem ICB, Via Campi Flegrei 34, I-80078 Naples, Italy;
6.Qingdao Natl Lab Marine Sci & Technol, Open Studio Druggabil Res Marine Nat Prod, 1 Wenhai Rd, Qingdao 266237, Peoples R China
推荐引用方式
GB/T 7714		 Ye, Fei,Li, Jing,Wu, Yu,et al. Sarinfacetamides A and B, Nitrogenous Diterpenoids with Tricyclo[6.3.1.0(1,5)]dodecane Scaffold from the South China Sea Soft Coral Sarcophyton infundibuliforme[J]. ORGANIC LETTERS,2018,20(9):2637-2640.
APA Ye, Fei.,Li, Jing.,Wu, Yu.,Zhu, Zheng-Dan.,Mollo, Ernesto.,...&Guo, Yue-Wei.(2018).Sarinfacetamides A and B, Nitrogenous Diterpenoids with Tricyclo[6.3.1.0(1,5)]dodecane Scaffold from the South China Sea Soft Coral Sarcophyton infundibuliforme.ORGANIC LETTERS,20(9),2637-2640.
MLA Ye, Fei,et al."Sarinfacetamides A and B, Nitrogenous Diterpenoids with Tricyclo[6.3.1.0(1,5)]dodecane Scaffold from the South China Sea Soft Coral Sarcophyton infundibuliforme".ORGANIC LETTERS 20.9(2018):2637-2640.

入库方式： OAI收割

来源：上海药物研究所

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