中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Cipaferoids A-C, Three Limonoids Represent Two Different Scaffolds from Cipadessa baccifera

文献类型:期刊论文

作者Yu, Jinhai2; Zhou, Bin2; Dalal, Seema1,3,4; Liu, Qunfang2; Cassera, Maria B.1,3,4; Yue, Jianmin2
刊名CHINESE JOURNAL OF CHEMISTRY
出版日期2018-02
卷号36期号:2页码:124-128
ISSN号1001-604X
关键词cipaferoids Cipadessa baccifera limonoids structural elucidation antimalarial activity
DOI10.1002/cjoc.201700627
文献子类Article
英文摘要Three limonoids cipaferoids A-C (1-3) representing two different scaffolds were isolated from Cipadessa baccifera. Their structures were completely assigned by spectroscopic data, CD exciton chirality method, and X-ray crystallography. Compounds 2 and 3 exhibited moderate antimalarial activity with IC50 values of 9.3 +/- 0.1 and 14.7 +/- 4.8 mol center dot L-1, respectively.
WOS关键词REARRANGED LIMONOIDS ; CINERASCENS ; CHEMISTRY ; TETRANORTRITERPENOIDS ; COCHINCHINENSIS ; SKELETONS ; MELIACEAE ; PLANTS ; SEEDS
资助项目National Natural Science Foundation of the People's Republic of China[21532007] ; National Natural Science Foundation of the People's Republic of China[81273398] ; National Natural Science Foundation of the People's Republic of China[81321092]
WOS研究方向Chemistry
语种英语
出版者WILEY-V C H VERLAG GMBH
WOS记录号WOS:000419774400005
源URL[http://119.78.100.183/handle/2S10ELR8/279940]  
专题天然药物化学研究室
中科院受体结构与功能重点实验室
新药研究国家重点实验室
通讯作者Yue, Jianmin
作者单位1.Univ Georgia, Dept Biochem & Mol Biol, Athens, GA 30602 USA
2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zu Chong Zhi Rd, Shanghai 201203, Peoples R China;
3.Virginia Polytech Inst & State Univ, Dept Biochem, MC 0308, Blacksburg, VA 24061 USA;
4.Virginia Polytech Inst & State Univ, Virginia Tech Ctr Drug Discovery, MC 0308, Blacksburg, VA 24061 USA;
推荐引用方式
GB/T 7714
Yu, Jinhai,Zhou, Bin,Dalal, Seema,et al. Cipaferoids A-C, Three Limonoids Represent Two Different Scaffolds from Cipadessa baccifera[J]. CHINESE JOURNAL OF CHEMISTRY,2018,36(2):124-128.
APA Yu, Jinhai,Zhou, Bin,Dalal, Seema,Liu, Qunfang,Cassera, Maria B.,&Yue, Jianmin.(2018).Cipaferoids A-C, Three Limonoids Represent Two Different Scaffolds from Cipadessa baccifera.CHINESE JOURNAL OF CHEMISTRY,36(2),124-128.
MLA Yu, Jinhai,et al."Cipaferoids A-C, Three Limonoids Represent Two Different Scaffolds from Cipadessa baccifera".CHINESE JOURNAL OF CHEMISTRY 36.2(2018):124-128.

入库方式: OAI收割

来源:上海药物研究所

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