Metal-free one-pot alpha-benzoxylation of benzylic alcohols with acids or aldehydes
文献类型：期刊论文
| 作者 | Zhu, Yefu; Zheng, Yong; Song, Weibin; Wei, Bole; Xuan, Lijiang1,2
|
| 刊名 | TETRAHEDRON LETTERS
 |
| 出版日期 | 2018-01-24 |
| 卷号 | 59期号:4页码:368-371 |
| 关键词 | nBu(4)NI TBHP alpha-Benzoxy ketones Cross-dehydrogenative coupling |
| ISSN号 | 0040-4039 |
| DOI | 10.1016/j.tetlet.2017.12.030 |
| 文献子类 | Article |
| 英文摘要 | A metal-free strategy has been developed for alpha-benzoxylation of benzylic alcohols with acids or aldehydes. The reaction proceeds via sequential oxidation and alpha-benzoxylation in one pot. Importantly, the reactions are performed in metal-free condition and utilize cheap aqueous TBHP as an oxidant, affording alpha-benzoxy ketones in moderate to good yields. (C) 2017 Elsevier Ltd. All rights reserved. |
| WOS关键词 | DEHYDROGENATIVE COUPLING CDC ; TERT-BUTYL HYDROPEROXIDE ; C-H BONDS ; CARBOXYLIC-ACIDS ; CARBONYL-COMPOUNDS ; TRANSITION-METAL ; EFFICIENT SYNTHESIS ; ACETOXY KETONES ; OXIDATION ; ACYLATION |
| 资助项目 | National Science & Technology major project "Key New Drug Creation and Manufacturing Program"[SIMM1601ZZ-03] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000424067200010 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/279948]  |
| 专题 | 上海中药现代化研究中心 中科院受体结构与功能重点实验室 新药研究国家重点实验室 |
| 通讯作者 | Xuan, Lijiang |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 501 Haike Rd,Zhangjiang Hitech Pk, Shanghai 201203, Peoples R China; 2.Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhu, Yefu,Zheng, Yong,Song, Weibin,et al. Metal-free one-pot alpha-benzoxylation of benzylic alcohols with acids or aldehydes[J]. TETRAHEDRON LETTERS,2018,59(4):368-371. |
| APA | Zhu, Yefu,Zheng, Yong,Song, Weibin,Wei, Bole,&Xuan, Lijiang.(2018).Metal-free one-pot alpha-benzoxylation of benzylic alcohols with acids or aldehydes.TETRAHEDRON LETTERS,59(4),368-371. |
| MLA | Zhu, Yefu,et al."Metal-free one-pot alpha-benzoxylation of benzylic alcohols with acids or aldehydes".TETRAHEDRON LETTERS 59.4(2018):368-371. |
入库方式： OAI收割
来源：上海药物研究所
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