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Chemical constituents from South China Sea soft coral Sinularia sp.

文献类型：期刊论文

作者Liang Linfu2; Li Yufen1; Zhen Tingting3; Yao Ligong1; Guo Yuewei1
刊名Chinese Traditional and Herbal Drugs
出版日期2017
卷号48期号:5页码:868-873
关键词Sinularia sp. axinysterol soft coral Sinularia sp. sterol lipid axinysterol methyl arachidonate
ISSN号0253-2670
其他题名中国南海短指软珊瑚Sinularia sp. 化学成分研究
文献子类Article
英文摘要Objective To investigate the chemical constituents of South China Sea soft coral Sinularia sp. Methods Compounds were isolated and purified by column chromatography on silica gel and Sephadex LH-20. Their structures were identified on the basis of mass(MS) and nuclear magnetic resonance(NMR) spectral data. Results Eleven compounds were isolated and identified as cholesterol(1), 3beta-hydroxycholest-5-en-7-one(2), 3beta-hydroxyergosta-5,24(28)-dien-7-one(3), campesterol(4), 24-methylenecholesterol(5), ergosterol peroxide(6), axinysterol(7), ergosterol(8),(3beta,4alpha,5alpha,8beta)-4-methylergost-24(28)-ene-3,8-diol(9), arachidonic acid(10), and methyl arachidonate(11). Conclusion Compounds 19 belong to sterols with three different types, while compounds 10 and 11 are unsaturated lipids. Moreover, compounds 7 and 11 are obtained from the soft corals of genus Sinularia sp. for the first time.
资助项目国家自然科学基金资助项目[00000000] ; 湖南省自然科学基金资助项目[00000000] ; 中国博士后科学基金资助项目[00000000] ; 中国科学院国家新药研究重点实验室项目[00000000] ; 中国科学院药物创新研究院自主部署科研项目[00000000]
WOS研究方向General & Internal Medicine (provided by Clarivate Analytics)
语种中文
CSCD记录号CSCD:5958543
源URL[http://119.78.100.183/handle/2S10ELR8/269210]  
专题天然药物化学研究室
通讯作者Guo Yuewei
作者单位1.State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.;
2.College of Material Science and Engineering, Central South University of Forestry and Technology, State Key Laboratory of Drug Research, Changsha, Hunan 410004, China.;
3.College of Material Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan 410004, China.
推荐引用方式
GB/T 7714		 Liang Linfu,Li Yufen,Zhen Tingting,et al. Chemical constituents from South China Sea soft coral Sinularia sp.[J]. Chinese Traditional and Herbal Drugs,2017,48(5):868-873.
APA Liang Linfu,Li Yufen,Zhen Tingting,Yao Ligong,&Guo Yuewei.(2017).Chemical constituents from South China Sea soft coral Sinularia sp..Chinese Traditional and Herbal Drugs,48(5),868-873.
MLA Liang Linfu,et al."Chemical constituents from South China Sea soft coral Sinularia sp.".Chinese Traditional and Herbal Drugs 48.5(2017):868-873.

入库方式： OAI收割

来源：上海药物研究所

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