Isoguanine octamer: From bowl to ball
文献类型：期刊论文
| 作者 | Gu, Hande; Wang, Jing; Leszczynski, Jerzy |
| 刊名 | CHEMICAL PHYSICS LETTERS
 |
| 出版日期 | 2007-09-13 |
| 卷号 | 445期号:4-6页码:243-245 |
| ISSN号 | 0009-2614 |
| DOI | 10.1016/j.cplett.2007.07.085 |
| 文献子类 | Article |
| 英文摘要 | Isoguanine (2-oxo-6-amino-guanine, isoG) can form the higher-order self-pairing ionophore structures by regulating the concentration of metal ions. The metal ion coordinated isoG-tetrads adopt bowl-like shape with the metal ion located at the bottom of the bowl. The present study of the formation of the H-bonded octamers ((isoG(4) M+)2(;) M+ = Na+, K+) illustrates that the bowl-shaped isoG4-M+ complexes are able to form the extraordinary ball-shaped octamers (isoG(4)-M+)(2) H-bonded through the H(N6) and N7 sites. A moderate energy barrier predicted for the process of separating the ball-shaped octamer into two bowl-shaped tetrads and the unique structural features of the octamer suggests a possibility towards construction of the self-assembled isoG nanostructures. (C) 2007 Elsevier B.V. All rights reserved. |
| WOS关键词 | QUARTETS ; DENSITY ; OLIGONUCLEOTIDES ; ISOGUANOSINE ; TETRAD |
| WOS研究方向 | Chemistry ; Physics |
| 语种 | 英语 |
| WOS记录号 | WOS:000250367100032 |
| 出版者 | ELSEVIER SCIENCE BV |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/273149]  |
| 专题 | 药物发现与设计中心 |
| 通讯作者 | Leszczynski, Jerzy |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China 2.Jackson State Univ, Computat Ctr Mol Struct & Interact, Dept Chem, Jackson, MS 39217 USA |
| 推荐引用方式 GB/T 7714 | Gu, Hande,Wang, Jing,Leszczynski, Jerzy. Isoguanine octamer: From bowl to ball[J]. CHEMICAL PHYSICS LETTERS,2007,445(4-6):243-245. |
| APA | Gu, Hande,Wang, Jing,&Leszczynski, Jerzy.(2007).Isoguanine octamer: From bowl to ball.CHEMICAL PHYSICS LETTERS,445(4-6),243-245. |
| MLA | Gu, Hande,et al."Isoguanine octamer: From bowl to ball".CHEMICAL PHYSICS LETTERS 445.4-6(2007):243-245. |
入库方式： OAI收割
来源：上海药物研究所
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