Two new phenols from Lysimachia patungensis
文献类型:期刊论文
作者 | Gao, Yuan-Yuan5; Zeng, Peng5; Jia, Cheng-Lin2,4; Zhang, Yong1,3; Zhang, Teng2,4; Jia, Qi5; Li, Yi-Ming5 |
刊名 | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
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出版日期 | 2017 |
卷号 | 19期号:1页码:28-34 |
关键词 | Primulaceae Lysimachia patungensis phenols methyl 3-(2-O--d-glucopyranosyl-3-hydroxy-5-methoxyphenyl) propionate myricetin-3 3 5-tri-O--l-rhamnopyranoside antioxidant activity |
ISSN号 | 1028-6020 |
DOI | 10.1080/10286020.2016.1183652 |
文献子类 | Article |
英文摘要 | Two new phenols, methyl 3-(2-O--d-glucopyranosyl-3-hydroxy-5-methoxyphenyl) propionate (1) and myricetin-3,3,5-tri-O--l-rhamnopyranoside (2), together with six known phenols compounds (3-8), were isolated from the whole plant of Lysimachia patungensis Hand.-Mazz. Their structures were elucidated on the basis of the interpretation of spectroscopic data, viz., ESI-MS, HR-TOF-MS, UV, IR, and NMR. All the known phenols were isolated from the genus Lysimachia for the first time. A preliminary bioassay revealed that compounds 3 and 7 exhibited significant protective effects against hydrogen peroxide-induced damage in human retinal endothelial cells (HRECs) with the concentration of 10M, respectively. Compound 1 showed moderate activity against the HRECs damage at 100M. |
WOS关键词 | CONSTITUENTS |
资助项目 | Natural Science Foundation of Shanghai, China[15ZR1441200] ; Youth Talent Sail Plan from Shanghai Committee of Science and Technology[16YF1414100] ; "Shanghai E-Research Institute of Bioactive Constituent in TCM" Plan[00000000] |
WOS研究方向 | Plant Sciences ; Chemistry ; Pharmacology & Pharmacy |
语种 | 英语 |
WOS记录号 | WOS:000392242300005 |
出版者 | TAYLOR & FRANCIS LTD |
源URL | [http://119.78.100.183/handle/2S10ELR8/275748] ![]() |
专题 | 药物发现与设计中心 |
通讯作者 | Zhang, Yong; Zhang, Teng; Jia, Qi |
作者单位 | 1.Chinese Acad Sci, Key Lab Receptor Res, Shanghai Inst Mat Med, Shanghai, Peoples R China 2.Shanghai Univ Tradit Chinese Med, Clin Res Inst Integrat Med, Shanghai 200437, Peoples R China; 3.Chinese Acad Sci, Drug Discovery & Design Ctr, Shanghai, Peoples R China; 4.Shanghai Univ Tradit Chinese Med, Yueyang Hosp, Shanghai 200437, Peoples R China; 5.Shanghai Univ Tradit Chinese Med, Sch Pharm, Shanghai 201203, Peoples R China; |
推荐引用方式 GB/T 7714 | Gao, Yuan-Yuan,Zeng, Peng,Jia, Cheng-Lin,et al. Two new phenols from Lysimachia patungensis[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2017,19(1):28-34. |
APA | Gao, Yuan-Yuan.,Zeng, Peng.,Jia, Cheng-Lin.,Zhang, Yong.,Zhang, Teng.,...&Li, Yi-Ming.(2017).Two new phenols from Lysimachia patungensis.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,19(1),28-34. |
MLA | Gao, Yuan-Yuan,et al."Two new phenols from Lysimachia patungensis".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 19.1(2017):28-34. |
入库方式: OAI收割
来源:上海药物研究所
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