中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Two new phenols from Lysimachia patungensis

文献类型:期刊论文

作者Gao, Yuan-Yuan5; Zeng, Peng5; Jia, Cheng-Lin2,4; Zhang, Yong1,3; Zhang, Teng2,4; Jia, Qi5; Li, Yi-Ming5
刊名JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
出版日期2017
卷号19期号:1页码:28-34
关键词Primulaceae Lysimachia patungensis phenols methyl 3-(2-O--d-glucopyranosyl-3-hydroxy-5-methoxyphenyl) propionate myricetin-3 3 5-tri-O--l-rhamnopyranoside antioxidant activity
ISSN号1028-6020
DOI10.1080/10286020.2016.1183652
文献子类Article
英文摘要Two new phenols, methyl 3-(2-O--d-glucopyranosyl-3-hydroxy-5-methoxyphenyl) propionate (1) and myricetin-3,3,5-tri-O--l-rhamnopyranoside (2), together with six known phenols compounds (3-8), were isolated from the whole plant of Lysimachia patungensis Hand.-Mazz. Their structures were elucidated on the basis of the interpretation of spectroscopic data, viz., ESI-MS, HR-TOF-MS, UV, IR, and NMR. All the known phenols were isolated from the genus Lysimachia for the first time. A preliminary bioassay revealed that compounds 3 and 7 exhibited significant protective effects against hydrogen peroxide-induced damage in human retinal endothelial cells (HRECs) with the concentration of 10M, respectively. Compound 1 showed moderate activity against the HRECs damage at 100M.
WOS关键词CONSTITUENTS
资助项目Natural Science Foundation of Shanghai, China[15ZR1441200] ; Youth Talent Sail Plan from Shanghai Committee of Science and Technology[16YF1414100] ; "Shanghai E-Research Institute of Bioactive Constituent in TCM" Plan[00000000]
WOS研究方向Plant Sciences ; Chemistry ; Pharmacology & Pharmacy
语种英语
WOS记录号WOS:000392242300005
出版者TAYLOR & FRANCIS LTD
源URL[http://119.78.100.183/handle/2S10ELR8/275748]  
专题药物发现与设计中心
通讯作者Zhang, Yong; Zhang, Teng; Jia, Qi
作者单位1.Chinese Acad Sci, Key Lab Receptor Res, Shanghai Inst Mat Med, Shanghai, Peoples R China
2.Shanghai Univ Tradit Chinese Med, Clin Res Inst Integrat Med, Shanghai 200437, Peoples R China;
3.Chinese Acad Sci, Drug Discovery & Design Ctr, Shanghai, Peoples R China;
4.Shanghai Univ Tradit Chinese Med, Yueyang Hosp, Shanghai 200437, Peoples R China;
5.Shanghai Univ Tradit Chinese Med, Sch Pharm, Shanghai 201203, Peoples R China;
推荐引用方式
GB/T 7714
Gao, Yuan-Yuan,Zeng, Peng,Jia, Cheng-Lin,et al. Two new phenols from Lysimachia patungensis[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2017,19(1):28-34.
APA Gao, Yuan-Yuan.,Zeng, Peng.,Jia, Cheng-Lin.,Zhang, Yong.,Zhang, Teng.,...&Li, Yi-Ming.(2017).Two new phenols from Lysimachia patungensis.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,19(1),28-34.
MLA Gao, Yuan-Yuan,et al."Two new phenols from Lysimachia patungensis".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 19.1(2017):28-34.

入库方式: OAI收割

来源:上海药物研究所

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