Eutypenoids A-C: Novel Pimarane Diterpenoids from the Arctic Fungus Eutypella sp. D-1
文献类型：期刊论文
| 作者 | Zhang, Liu-Qiang2; Chen, Xiao-Chong2; Chen, Zhao-Qiang3; Wang, Gui-Min3; Zhu, Shi-Guo2; Yang, Yi-Fu2; Chen, Kai-Xian2,3 ; Liu, Xiao-Yu1; Li, Yi-Ming2
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| 刊名 | MARINE DRUGS
 |
| 出版日期 | 2016-03 |
| 卷号 | 14期号:3 |
| 关键词 | eutypenoid Arctic fungi Eutypella novel pimarane diterpenes immunosuppressive effect |
| ISSN号 | 1660-3397 |
| DOI | 10.3390/md14030044 |
| 文献子类 | Article |
| 英文摘要 | Eutypenoids A-C (1-3), pimarane diterpenoid alkaloid and two ring A rearranged pimarane diterpenoids, were isolated from the culture of Eutypella sp. D-1 obtained from high-latitude soil of the Arctic. Their structures, including absolute configurations, were authenticated on the basis of the mass spectroscopy (MS), nuclear magnetic resonance (NMR), X-ray crystallography, and electronic circular dichroism (ECD) analysis. The immunosuppressive effects of eutypenoids A-C (1-3) were studied using a ConA-induced splenocyte proliferation model, which suggested that 2 exhibited potent immunosuppressive activities. |
| WOS关键词 | MARINE NATURAL-PRODUCTS ; ELECTRONIC CIRCULAR-DICHROISM ; SCOPARIA FS26 ; CYTOCHALASINS ; MACROPHAGES |
| 资助项目 | National High Technology Research and Development Program of China (863 program)[2013AA093003] ; Program for Professors of Special Appointment (Eastern Scholar) in the Shanghai Institutions of Higher Learning[2012-90] ; National Natural Science Foundation of China[81173518] ; National Natural Science Foundation of China[81261120567] |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000373701200015 |
| 出版者 | MDPI AG |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276113]  |
| 专题 | 药物发现与设计中心 |
| 通讯作者 | Liu, Xiao-Yu; Li, Yi-Ming |
| 作者单位 | 1.Second Mil Med Univ, Dept Biochem & Mol Biol, 800 Xiangyin Rd, Shanghai 200433, Peoples R China 2.Shanghai Univ Tradit Chinese Med, Sch Pharm, 1200 Cailun Rd, Shanghai 201203, Peoples R China; 3.Chinese Acad Sci, Shanghai Inst Med, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Zhang, Liu-Qiang,Chen, Xiao-Chong,Chen, Zhao-Qiang,et al. Eutypenoids A-C: Novel Pimarane Diterpenoids from the Arctic Fungus Eutypella sp. D-1[J]. MARINE DRUGS,2016,14(3). |
| APA | Zhang, Liu-Qiang.,Chen, Xiao-Chong.,Chen, Zhao-Qiang.,Wang, Gui-Min.,Zhu, Shi-Guo.,...&Li, Yi-Ming.(2016).Eutypenoids A-C: Novel Pimarane Diterpenoids from the Arctic Fungus Eutypella sp. D-1.MARINE DRUGS,14(3). |
| MLA | Zhang, Liu-Qiang,et al."Eutypenoids A-C: Novel Pimarane Diterpenoids from the Arctic Fungus Eutypella sp. D-1".MARINE DRUGS 14.3(2016). |
入库方式： OAI收割
来源：上海药物研究所
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