Drug-drug co-crystallization presents a new opportunity for the development of stable vitamins
文献类型：期刊论文
| 作者 | Wang, Jian-Rong ; Yu, Qihui; Dai, Wenjuan; Mei, Xuefeng
|
| 刊名 | CHEMICAL COMMUNICATIONS
 |
| 出版日期 | 2016 |
| 卷号 | 52期号:17页码:3572-3575 |
| ISSN号 | 1359-7345 |
| DOI | 10.1039/c5cc10297a |
| 文献子类 | Article |
| 英文摘要 | Drug-drug co-crystallization could realize combination drugs at a molecular level. Two polymorphic co-crystals between VD2 and VD3 were successfully designed and synthesized. These enantiotropic polymorphs exhibit significantly different physicochemical stabilities. |
| WOS关键词 | FIXED-DOSE COMBINATIONS ; CO-CRYSTALS ; ERGOCALCIFEROL VITAMIN-D2 ; IMPROVED MEDICINES ; NICOTINAMIDE ; POLYMORPHISM ; DEGRADATION ; STABILITY ; ACID ; PATH |
| 资助项目 | National Natural Science Foundation of China[81273479] ; National Natural Science Foundation of China[81402898] ; CAS Key Technology Talent Program[00000000] ; Youth Innovation Promotion Association CAS[00000000] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000371026700028 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276247]  |
| 专题 | 药物质量控制与固体化学研究中心 |
| 通讯作者 | Mei, Xuefeng |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, Pharmaceut Analyt & Solid State Chem Res Ctr, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Jian-Rong,Yu, Qihui,Dai, Wenjuan,et al. Drug-drug co-crystallization presents a new opportunity for the development of stable vitamins[J]. CHEMICAL COMMUNICATIONS,2016,52(17):3572-3575. |
| APA | Wang, Jian-Rong,Yu, Qihui,Dai, Wenjuan,&Mei, Xuefeng.(2016).Drug-drug co-crystallization presents a new opportunity for the development of stable vitamins.CHEMICAL COMMUNICATIONS,52(17),3572-3575. |
| MLA | Wang, Jian-Rong,et al."Drug-drug co-crystallization presents a new opportunity for the development of stable vitamins".CHEMICAL COMMUNICATIONS 52.17(2016):3572-3575. |
入库方式： OAI收割
来源：上海药物研究所
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