A highly efficient approach to unnatural amino-acids containing 3-hydroxyoxindole skeleton via a one-pot, three-component procedure
文献类型：期刊论文
| 作者 | Huang, Huang1; Xu, Yong3; Mao, Fei1; Zhu, Jin1; Jiang, Hualiang1,2 ; Li, Jian1
|
| 刊名 | TETRAHEDRON LETTERS
 |
| 出版日期 | 2015-01-21 |
| 卷号 | 56期号:4页码:586-589 |
| 关键词 | Unnatural amino-acid 3-Hydroxyoxindole Multicomponent reaction Isatin Benzophenone imine |
| ISSN号 | 0040-4039 |
| DOI | 10.1016/j.tetlet.2014.12.011 |
| 文献子类 | Article |
| 英文摘要 | An efficient approach for the synthesis of biologically interesting unnatural amino-acids containing 3-hydrooxindole skeleton has been developed. The strategy features a catalyst-free, one-pot, three-component process involving the formation of two new quaternary centers in high yields and with a broad substrate scope. (C) 2014 Elsevier Ltd. All rights reserved. |
| WOS关键词 | MULTICOMPONENT REACTIONS ; OXINDOLE ALKALOIDS ; STRECKER REACTIONS ; TRANSITION-METAL ; DERIVATIVES ; CATALYSTS ; HETEROCYCLES ; ALKYLATION ; COMPLEXES ; ALCOHOLS |
| 资助项目 | National Natural Science Foundation of China[21222211] ; National Natural Science Foundation of China[21372001] ; National Natural Science Foundation of China[91313303] ; Program for New Century Excellent Talents in University[NCET-12-0853] ; Fundamental Research Funds for the Central Universities[00000000] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000348337700004 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276667]  |
| 专题 | 药物发现与设计中心 |
| 通讯作者 | Mao, Fei |
| 作者单位 | 1.E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab New Drug Design, Shanghai 200237, Peoples R China; 2.Chinese Acad Sci, Shanghai Inst Mat Med, Drug Discovery & Design Ctr, Shanghai 201203, Peoples R China 3.Humanwell Healthcare Grp Co Ltd, Wuhan 430075, Hubei, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Huang, Huang,Xu, Yong,Mao, Fei,et al. A highly efficient approach to unnatural amino-acids containing 3-hydroxyoxindole skeleton via a one-pot, three-component procedure[J]. TETRAHEDRON LETTERS,2015,56(4):586-589. |
| APA | Huang, Huang,Xu, Yong,Mao, Fei,Zhu, Jin,Jiang, Hualiang,&Li, Jian.(2015).A highly efficient approach to unnatural amino-acids containing 3-hydroxyoxindole skeleton via a one-pot, three-component procedure.TETRAHEDRON LETTERS,56(4),586-589. |
| MLA | Huang, Huang,et al."A highly efficient approach to unnatural amino-acids containing 3-hydroxyoxindole skeleton via a one-pot, three-component procedure".TETRAHEDRON LETTERS 56.4(2015):586-589. |
入库方式： OAI收割
来源：上海药物研究所
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