Pd-catalyzed alpha-selective C(sp(3))-H acetoxylation of amides through an unusual cyclopalladation mechanism
文献类型：期刊论文
| 作者 | Wang, Meining1,2; Yang, Yang3; Fan, Zhoulong1,2; Cheng, Zhen4; Zhu, Weiliang3 ; Zhang, Ao1,2
|
| 刊名 | CHEMICAL COMMUNICATIONS
 |
| 出版日期 | 2015 |
| 卷号 | 51期号:15页码:3219-3222 |
| ISSN号 | 1359-7345 |
| DOI | 10.1039/c4cc09576f |
| 文献子类 | Article |
| 英文摘要 | We report the first example of Pd-catalyzed site-selective alpha-C(sp(3))-H oxidation/acetoxylation of amides through an unusual [4,6]-bicyclic metallacycle intermediate with 1-aminoanthraquinone as a new bidentate directing group. In addition to the distinctmechanism and high efficiency, the reaction is highly appealing due to the ample commercial source, low-cost, as well as easy removal and recycling of the auxiliary group. |
| WOS关键词 | C-H BONDS ; UNACTIVATED C(SP(3))-H ; DIRECTING GROUP ; C(SP(2))-H BONDS ; ACID DERIVATIVES ; DIRECT ARYLATION ; METHYL-GROUPS ; FUNCTIONALIZATION ; ACTIVATION ; OXIDATION |
| 资助项目 | Chinese National Natural Science Foundation[81430080] ; Chinese National Natural Science Foundation[81125021] ; Chinese National Natural Science Foundation[81373277] ; Major State Basic Research Development Program[2015CB910603] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000349324200048 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/276761]  |
| 专题 | 药物发现与设计中心 药物化学研究室 上海药物代谢研究中心 |
| 通讯作者 | Cheng, Zhen |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Receptor Res, Shanghai 201203, Peoples R China; 2.Chinese Acad Sci, SIMM, SOMCL, Shanghai 201203, Peoples R China; 3.Chinese Acad Sci, SIMM, Drug Discovery & Design Ctr, Shanghai 201203, Peoples R China; 4.Stanford Univ, Sch Med, Dept Radiol, Stanford, CA 94305 USA |
| 推荐引用方式 GB/T 7714 | Wang, Meining,Yang, Yang,Fan, Zhoulong,et al. Pd-catalyzed alpha-selective C(sp(3))-H acetoxylation of amides through an unusual cyclopalladation mechanism[J]. CHEMICAL COMMUNICATIONS,2015,51(15):3219-3222. |
| APA | Wang, Meining,Yang, Yang,Fan, Zhoulong,Cheng, Zhen,Zhu, Weiliang,&Zhang, Ao.(2015).Pd-catalyzed alpha-selective C(sp(3))-H acetoxylation of amides through an unusual cyclopalladation mechanism.CHEMICAL COMMUNICATIONS,51(15),3219-3222. |
| MLA | Wang, Meining,et al."Pd-catalyzed alpha-selective C(sp(3))-H acetoxylation of amides through an unusual cyclopalladation mechanism".CHEMICAL COMMUNICATIONS 51.15(2015):3219-3222. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。