An Efficient One-Pot Synthesis of Substituted 2-Aminothiophenes via Three-Component Gewald Reaction Catalyzed by L-Proline
文献类型：期刊论文
| 作者 | Wang, Tao2,4; Huang, Xian-Gui2,4; Liu, Jia2,4 ; Li, Bo3; Wu, Jin-Jin2; Chen, Kai-Xian3; Zhu, Wei-Liang1,2; Xu, Xiao-Yong2,4; Zeng, Bu-Bing2,4
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| 刊名 | SYNLETT
 |
| 出版日期 | 2010-06 |
| 期号 | 9页码:1351-1354 |
| 关键词 | Gewald reaction 2-aminothiophene one-pot multi-component Knoevenagel reaction |
| ISSN号 | 0936-5214 |
| DOI | 10.1055/s-0029-1219917 |
| 文献子类 | Article |
| 英文摘要 | An efficient one-pot procedure for the direct catalytic synthesis of substituted 2-aminothiophenes catalyzed by L-proline under mild reaction conditions has been developed. A variety of functionalized 2-aminothiophene scaffolds were assembled in high yields by this catalytic protocol. Low catalyst loading, simple procedure, and high yields are the important attributes of this methodology. |
| WOS关键词 | ORGANOCATALYTIC MULTICOMPONENT REACTIONS ; ALLOSTERIC ENHANCERS ; THIOPHENES ; INHIBITORS ; CYCLOADDITION ; BINDING ; SULFUR |
| 资助项目 | Science & Technology Commission of Shanghai Municipality[064319022] ; 111 Project[B07023] ; National '863' Project of China[2006AA609Z447] ; National '863' Project of China[2007AA02Z301] ; Shanghai Pujiang Program[05PJ14035] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000278408800012 |
| 出版者 | GEORG THIEME VERLAG KG |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/278895]  |
| 专题 | 药物发现与设计中心 |
| 通讯作者 | Wang, Tao |
| 作者单位 | 1.Shanghai Inst Mat Med, Drug Discovery & Design Ctr, Shanghai 201203, Peoples R China; 2.E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China; 3.Shanghai Univ Tradit Chinese Med, Shanghai 201203, Peoples R China 4.Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China; |
| 推荐引用方式 GB/T 7714 | Wang, Tao,Huang, Xian-Gui,Liu, Jia,et al. An Efficient One-Pot Synthesis of Substituted 2-Aminothiophenes via Three-Component Gewald Reaction Catalyzed by L-Proline[J]. SYNLETT,2010(9):1351-1354. |
| APA | Wang, Tao.,Huang, Xian-Gui.,Liu, Jia.,Li, Bo.,Wu, Jin-Jin.,...&Zeng, Bu-Bing.(2010).An Efficient One-Pot Synthesis of Substituted 2-Aminothiophenes via Three-Component Gewald Reaction Catalyzed by L-Proline.SYNLETT(9),1351-1354. |
| MLA | Wang, Tao,et al."An Efficient One-Pot Synthesis of Substituted 2-Aminothiophenes via Three-Component Gewald Reaction Catalyzed by L-Proline".SYNLETT .9(2010):1351-1354. |
入库方式： OAI收割
来源：上海药物研究所
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