PKCs promotes ceramide-induced apoptosis in PC12 cells by decreasing the ratio of Bcl2/Bax involved in a Ca~(2+)- dependent pathway and NF-κB activation
文献类型：会议论文
| 作者 | Jin DZ(金道忠); Zhu XZ(朱兴族) |
| 出版日期 | 2005-10-01 |
| 关键词 | ceramide PKC Bcl2 Bax Ca2+ IκB |
| 卷号 | 21 |
| 页码 | 1 |
| 英文摘要 | This study investigated the rele of PKCs on ceramide-induced apoptosis in Rat phaeochromocytoma PC 12 cells. Exogenous C6-ceramide induced apoptosis in PC 12 cells in a concentration-dependent way (5-20μmol/L). It failed to change the anti-apoptosis protein Bc12 and proapoptosis protein Bax expression at 12 h. Phorbol 12-myristate 13-acetate (PMA), a PKCs activator, failed to change the survive of PC12 |
| 会议录 | 中国神经科学学会第六届学术会议暨学会成立十周年庆祝大会论文摘要汇编
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| 文献子类 | Article |
| 语种 | 英语 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/267570]  |
| 专题 | 药理学第二研究室 |
| 推荐引用方式 GB/T 7714 | Jin DZ,Zhu XZ. PKCs promotes ceramide-induced apoptosis in PC12 cells by decreasing the ratio of Bcl2/Bax involved in a Ca~(2+)- dependent pathway and NF-κB activation[C]. 见:. |
入库方式： OAI收割
来源：上海药物研究所
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