Progress in clinical studies of huperzine A on improvement of cognitive function
文献类型：期刊论文
| 作者 | Wang Xujie; Zhang Haiyan
|
| 刊名 | Chinese Journal of New Drugs and Clinical Remedies
 |
| 出版日期 | 2012 |
| 卷号 | 31期号:12页码:707-712 |
| 关键词 | huperzine A Alzheimer disease dementia, vascular delirium, dementia, amnestic, cognitive disorders |
| ISSN号 | 1007-7669 |
| 其他题名 | 石杉碱甲改善认知功能的临床研究进展 |
| 文献子类 | Review |
| 英文摘要 | Cognitive impairment is the key feature of various types of dementia, among which Alzheimer's disease (AD) is the most common form. Huperzine A, isolated from Chinese traditional herb Huperzia serrata, is a potent, reversible and highly selective acetylcholinesterase inhibitor, which has been acknowledged to possess the capability to improve cognitive function of AD patients. With the continuous expansion of the clinical applications, huperzine A has been reported to have pretty good efficacy in the treatment of vascular dementia and cognitive impairment caused by schizophrenia, Parkinson's disease, diabetes and other pathogenesis, indicating a very broad prospects for clinical application. This review summarized the progress in clinical studies of huperzine A administration alone or in combination with other drugs on the treatment of patients with cognitive impairment, which could provide important clues and evidences to the rational application of huperzine A in the future. |
| WOS研究方向 | Pharmacology & Pharmacy ; Neurosciences & Neurology (provided by Clarivate Analytics) |
| 语种 | 中文 |
| CSCD记录号 | CSCD:4751098 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/267803]  |
| 专题 | 药理学第二研究室 |
| 通讯作者 | Zhang Haiyan |
| 作者单位 | State Key Laboratory of Drug Research, Shanghai Insititute of Materia Medica, Chinese Academy of Sciences, SHANGHAI 201203, China. |
| 推荐引用方式 GB/T 7714 | Wang Xujie,Zhang Haiyan. Progress in clinical studies of huperzine A on improvement of cognitive function[J]. Chinese Journal of New Drugs and Clinical Remedies,2012,31(12):707-712. |
| APA | Wang Xujie,&Zhang Haiyan.(2012).Progress in clinical studies of huperzine A on improvement of cognitive function.Chinese Journal of New Drugs and Clinical Remedies,31(12),707-712. |
| MLA | Wang Xujie,et al."Progress in clinical studies of huperzine A on improvement of cognitive function".Chinese Journal of New Drugs and Clinical Remedies 31.12(2012):707-712. |
入库方式： OAI收割
来源：上海药物研究所
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