TREK1 potassium channels and depression
文献类型：期刊论文
| 作者 | Ye Dongqing1; Zhang Zhijun1; Li Yang2
|
| 刊名 | Acta Pharmaceutica Sinica
 |
| 出版日期 | 2012 |
| 卷号 | 47期号:11页码:1403-1408 |
| 关键词 | TREK1 two pore potassium channel TREK1 depression neural protection plasticity |
| ISSN号 | 0513-4870 |
| 其他题名 | TREK1钾通道与抑郁症 |
| 文献子类 | Review |
| 英文摘要 | Major depression disorder is an increasing heavy burden in modern society, but its pathological mechanism is still vague. Recent evidence indicated that two pore potassium channel, TREK1, is one of the important drug targets of antidepressants. The structural and functional research progress of TREK1 potassium channel were reviewed with an emphasis on its roles in anti-depression, neuronal protection, and neuronal plasticity. The complicated interactions between TREK1 potassium channel and monoamine transmitters- receptors were also reviewed and future directions to explore the underline mechanism were also discussed. |
| WOS研究方向 | Pharmacology & Pharmacy (provided by Clarivate Analytics) |
| 语种 | 中文 |
| CSCD记录号 | CSCD:4665952 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/267815]  |
| 专题 | 药理学第一研究室 药理学第二研究室 |
| 通讯作者 | Li Yang |
| 作者单位 | 1.Institute of Neurology and Psychiatry, Southeast University, Nanjing, Jiangsu 210009, China.; 2.Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. |
| 推荐引用方式 GB/T 7714 | Ye Dongqing,Zhang Zhijun,Li Yang. TREK1 potassium channels and depression[J]. Acta Pharmaceutica Sinica,2012,47(11):1403-1408. |
| APA | Ye Dongqing,Zhang Zhijun,&Li Yang.(2012).TREK1 potassium channels and depression.Acta Pharmaceutica Sinica,47(11),1403-1408. |
| MLA | Ye Dongqing,et al."TREK1 potassium channels and depression".Acta Pharmaceutica Sinica 47.11(2012):1403-1408. |
入库方式： OAI收割
来源：上海药物研究所
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