Progresses on prion proteins
文献类型：期刊论文
| 作者 | LIN DongHai1; WEN Yi2 |
| 刊名 | Scientia Sinica Chimica
 |
| 出版日期 | 2011 |
| 卷号 | 41期号:4页码:683-698 |
| 关键词 | transmissible spongiform encephalopathies prion conformational conversion |
| ISSN号 | 1674-7224 |
| 其他题名 | 朊病毒蛋白prion的研究进展 |
| 文献子类 | Review |
| 英文摘要 | Transmissible spongiform encephalopathies are a family of fatal neurodegenerative disorders.The pathogen has been identified as the abnormal isoform of the host-derived prion protein.The molecular mechanism of the conformational conversion of the prion protein is unclear so far.However,much valuable information closely related to the conformational change has been obtained by means of physical,chemical and biological techniques.Recent progresses on three-dimensional structures,dynamics,unfolding and intermolecular interactions of prion proteins are reviewed herein,together with novel results about the solution structure and dynamics of the rabbit prion protein achieved from our laboratory. |
| 资助项目 | 国家自然科学基金[00000000] ; 上海市优秀学科带头人计划[00000000] ; 中国科学院知识创新工程重要方向项目[00000000] ; 国家重点基础研究发展计划973蛋白质重大研究计划项目[00000000] |
| WOS研究方向 | Microbiology (provided by Clarivate Analytics) |
| 语种 | 中文 |
| CSCD记录号 | CSCD:4268347 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/267879]  |
| 专题 | 分析化学研究室 |
| 作者单位 | 1.Laboratory of Structural Biology,Department of Chemical Biology,College of Chemistry & Chemical Engineering,Xiamen University, Xiamen, Fujian 361005, China.; 2.Bio-NMR Laboratory,Shanghai Institute of Materia Medica,Chinese Academy of Sciences, Shanghai 201203, China. |
| 推荐引用方式 GB/T 7714 | LIN DongHai,WEN Yi. Progresses on prion proteins[J]. Scientia Sinica Chimica,2011,41(4):683-698. |
| APA | LIN DongHai,&WEN Yi.(2011).Progresses on prion proteins.Scientia Sinica Chimica,41(4),683-698. |
| MLA | LIN DongHai,et al."Progresses on prion proteins".Scientia Sinica Chimica 41.4(2011):683-698. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。