中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
EFFECTS OF JITAI TABLETS ON IMMUNE FUNCTIONIN MORPHINE DEPENDENT MICE

文献类型:期刊论文

作者Wang Yuhua1; Tao Yimin2; Chen Jie2; Xu Xuejun2; Chi Zhiqiang2; Liu Jinggen2
刊名Chinese Journal of Drug Dependence
出版日期2011
卷号20期号:1页码:22-25
关键词Jitai tablet morphine dependence immune function
ISSN号1007-9718
其他题名济泰片对吗啡损伤小鼠免疫功能的影响
文献子类Article
英文摘要Objective:To observe the effects of Jitai tablets on immune function in morphine dependent mice. Methods:A chronic morphine dependent model was established by repeated subcutaneous injection of morphine in mice. Thymus and spleen index were determined. Carbon clearance test, dinitrofluorobenzene-induced delayed type hypersensitivity test(DTH) and hemolysin test were employed to evaluate the immunomodulating effects of Jitai tablets in morphine dependent mice. Results:Jitai tablets(0.30 g·kg-1 and 0.60 g·kg-1) significantly increased clearance index(K), phagocytic index(alpha), ear swelling, hemolysin level(HC50 value) as well as thymus and spleen index in morphine dependent mice(P<0.01). Conclusion:Jitai tablets can significantly enhance the immune function of morphine dependent mice
资助项目国家支撑计划[00000000]
WOS研究方向Pharmacology & Pharmacy (provided by Clarivate Analytics)
语种中文
CSCD记录号CSCD:4162593
源URL[http://119.78.100.183/handle/2S10ELR8/267889]  
专题药理学第二研究室
通讯作者Liu Jinggen
作者单位1.School of Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu 210009, China.;
2.State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, China.
推荐引用方式
GB/T 7714
Wang Yuhua,Tao Yimin,Chen Jie,et al. EFFECTS OF JITAI TABLETS ON IMMUNE FUNCTIONIN MORPHINE DEPENDENT MICE[J]. Chinese Journal of Drug Dependence,2011,20(1):22-25.
APA Wang Yuhua,Tao Yimin,Chen Jie,Xu Xuejun,Chi Zhiqiang,&Liu Jinggen.(2011).EFFECTS OF JITAI TABLETS ON IMMUNE FUNCTIONIN MORPHINE DEPENDENT MICE.Chinese Journal of Drug Dependence,20(1),22-25.
MLA Wang Yuhua,et al."EFFECTS OF JITAI TABLETS ON IMMUNE FUNCTIONIN MORPHINE DEPENDENT MICE".Chinese Journal of Drug Dependence 20.1(2011):22-25.

入库方式: OAI收割

来源:上海药物研究所

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