EFFECTS OF JITAI TABLETS ON IMMUNE FUNCTIONIN MORPHINE DEPENDENT MICE
文献类型:期刊论文
作者 | Wang Yuhua1; Tao Yimin2; Chen Jie2; Xu Xuejun2; Chi Zhiqiang2![]() ![]() |
刊名 | Chinese Journal of Drug Dependence
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出版日期 | 2011 |
卷号 | 20期号:1页码:22-25 |
关键词 | Jitai tablet morphine dependence immune function |
ISSN号 | 1007-9718 |
其他题名 | 济泰片对吗啡损伤小鼠免疫功能的影响 |
文献子类 | Article |
英文摘要 | Objective:To observe the effects of Jitai tablets on immune function in morphine dependent mice. Methods:A chronic morphine dependent model was established by repeated subcutaneous injection of morphine in mice. Thymus and spleen index were determined. Carbon clearance test, dinitrofluorobenzene-induced delayed type hypersensitivity test(DTH) and hemolysin test were employed to evaluate the immunomodulating effects of Jitai tablets in morphine dependent mice. Results:Jitai tablets(0.30 g·kg-1 and 0.60 g·kg-1) significantly increased clearance index(K), phagocytic index(alpha), ear swelling, hemolysin level(HC50 value) as well as thymus and spleen index in morphine dependent mice(P<0.01). Conclusion:Jitai tablets can significantly enhance the immune function of morphine dependent mice |
资助项目 | 国家支撑计划[00000000] |
WOS研究方向 | Pharmacology & Pharmacy (provided by Clarivate Analytics) |
语种 | 中文 |
CSCD记录号 | CSCD:4162593 |
源URL | [http://119.78.100.183/handle/2S10ELR8/267889] ![]() |
专题 | 药理学第二研究室 |
通讯作者 | Liu Jinggen |
作者单位 | 1.School of Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu 210009, China.; 2.State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, China. |
推荐引用方式 GB/T 7714 | Wang Yuhua,Tao Yimin,Chen Jie,et al. EFFECTS OF JITAI TABLETS ON IMMUNE FUNCTIONIN MORPHINE DEPENDENT MICE[J]. Chinese Journal of Drug Dependence,2011,20(1):22-25. |
APA | Wang Yuhua,Tao Yimin,Chen Jie,Xu Xuejun,Chi Zhiqiang,&Liu Jinggen.(2011).EFFECTS OF JITAI TABLETS ON IMMUNE FUNCTIONIN MORPHINE DEPENDENT MICE.Chinese Journal of Drug Dependence,20(1),22-25. |
MLA | Wang Yuhua,et al."EFFECTS OF JITAI TABLETS ON IMMUNE FUNCTIONIN MORPHINE DEPENDENT MICE".Chinese Journal of Drug Dependence 20.1(2011):22-25. |
入库方式: OAI收割
来源:上海药物研究所
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