Mitochondrial permeability transition pore and neurologic disease
文献类型：期刊论文
| 作者 | ZHENG Chunyan; ZHANG Haiyan
|
| 刊名 | Chinese Journal of New Drugs and Clinical Remedies
 |
| 出版日期 | 2008 |
| 卷号 | 27期号:6页码:454-461 |
| 关键词 | 线粒体 细胞死亡 神经系统疾病 线粒体通透性季 |
| ISSN号 | 1007-7669 |
| 其他题名 | 线粒体通透性转变孔道与神经系统疾病 |
| 文献子类 | Article |
| 英文摘要 | Mitochondrial permeability transition pore (MPTP) is speculated to be composed of voltage- dependent anion channel (VDAC),adenine nucleotide translocator (ANT),and cyclophilin-D CYP-D.Many factors including small molecules,signaling kinase pathways,and protein-protein interaction could modulate the opening of this pore.The opening of the pore could increase the permeability of mitochondrial inner membranes to ions and solutes thereby results in mitochondrial dysfunction,which may be involved in the pathology of neurologic diseases. |
| WOS研究方向 | Neurosciences & Neurology (provided by Clarivate Analytics) |
| 语种 | 中文 |
| CSCD记录号 | CSCD:3313425 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/268046]  |
| 专题 | 药理学第二研究室 |
| 通讯作者 | ZHANG Haiyan |
| 作者单位 | 中国科学院上海药物研究所, 新药研究国家重点实验室, 上海 201203, 中国. |
| 推荐引用方式 GB/T 7714 | ZHENG Chunyan,ZHANG Haiyan. Mitochondrial permeability transition pore and neurologic disease[J]. Chinese Journal of New Drugs and Clinical Remedies,2008,27(6):454-461. |
| APA | ZHENG Chunyan,&ZHANG Haiyan.(2008).Mitochondrial permeability transition pore and neurologic disease.Chinese Journal of New Drugs and Clinical Remedies,27(6),454-461. |
| MLA | ZHENG Chunyan,et al."Mitochondrial permeability transition pore and neurologic disease".Chinese Journal of New Drugs and Clinical Remedies 27.6(2008):454-461. |
入库方式： OAI收割
来源：上海药物研究所
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