Isolation and structure identification of bioactive fraction AM105-Ⅱ from marine actinomycete
文献类型：期刊论文
| 作者 | HUANG Huiqin2; GUO Fujiang1; HU Yonghua2; FANG Zhe2; REN Lichen2; BAO Shixiang2 |
| 刊名 | Chinese Journal of Marine Drugs
 |
| 出版日期 | 2006 |
| 卷号 | 25期号:4页码:17-21 |
| 关键词 | rnicromonospor antibiotic isolation and purificat ion4astructure identification rifamyein |
| ISSN号 | 1002-3461 |
| 其他题名 | 海洋放线菌活性组分AM105-Ⅱ的分离与结构鉴定 |
| 文献子类 | Article |
| 英文摘要 | Objective To isolate and idenlify the anti-MRSA bioactive fraction from the fermentation broth of the marine-derived actinomycete AM105. Methods By means of silica gel column chromatography, preparative TLC and Sephadex LH20 column chromatography, the bioaetive component was purified. The structure was determined by the spectral methods. Results and Conclusion The bioaetive component AM105-Ⅱ was purified and the spectra showed that AM105-Ⅱ was composed of rifamyein S and its isomer, named isorifamyein S, which is a novel structure compound. Its antibacterial activity is better than rifamyein SV according to MIC. |
| WOS研究方向 | Pharmacology & Pharmacy ; Microbiology (provided by Clarivate Analytics) |
| 语种 | 中文 |
| CSCD记录号 | CSCD:2607012 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/268192]  |
| 专题 | 药理学第二研究室 |
| 作者单位 | 1.Shanghai Institute of Material Medica, Chinese Academy of Sciences, Shanghai 201203, China. 2.Institute of Tropical Bioscience ＆ Biotechnology, National Key Biotechnology Laboratory of Tropical Crops, Chinese Academy of Tropical Agricultural Sciences, Haikou, Hainan 571101, China.; |
| 推荐引用方式 GB/T 7714 | HUANG Huiqin,GUO Fujiang,HU Yonghua,et al. Isolation and structure identification of bioactive fraction AM105-Ⅱ from marine actinomycete[J]. Chinese Journal of Marine Drugs,2006,25(4):17-21. |
| APA | HUANG Huiqin,GUO Fujiang,HU Yonghua,FANG Zhe,REN Lichen,&BAO Shixiang.(2006).Isolation and structure identification of bioactive fraction AM105-Ⅱ from marine actinomycete.Chinese Journal of Marine Drugs,25(4),17-21. |
| MLA | HUANG Huiqin,et al."Isolation and structure identification of bioactive fraction AM105-Ⅱ from marine actinomycete".Chinese Journal of Marine Drugs 25.4(2006):17-21. |
入库方式： OAI收割
来源：上海药物研究所
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