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Regulation of metabolism and apoptotic signal by ceramide
文献类型：期刊论文
| 作者 | JIN DaoZhong; ZHU XingZu |
| 刊名 | Chinese Bulletin of Life Sciences
 |
| 出版日期 | 2006 |
| 卷号 | 18期号:5页码:481-486 |
| 关键词 | ceramide apoptosis kinase suppressor of Ras c-Jun N-terminal kinase PKCzeta protein phosphatase |
| ISSN号 | 1004-0374 |
| 其他题名 | 神经酰胺代谢及凋亡信号调节 |
| 文献子类 | Review |
| 英文摘要 | The sphingomyelin pathway is a ubiquitous signaling system, in which ceramide acts as a second messenger. Some enzymes are involved in generation or abolishment of ceramide. In several cell systems ceramide links to the stress-activated protein kinase, c-Jun N-terminal kinase, kinase suppressor of Ras, PKCzeta, protein phosphatase 1, protein phosphatase 2A to signal apoptosis. The engagement of the sphingomyelin pathway in signaling apoptosis is tightly regulated to some stress related diseases and tumors. This review describes the known role of ceramide and the metabolite in stress response cascade and apoptosis. |
| WOS研究方向 | Biochemistry & Molecular Biology ; Cell Biology (provided by Clarivate Analytics) |
| 语种 | 中文 |
| CSCD记录号 | CSCD:2547952 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/268260]  |
| 专题 | 药理学第二研究室 |
| 作者单位 | Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, China. |
| 推荐引用方式 GB/T 7714 | JIN DaoZhong,ZHU XingZu. Regulation of metabolism and apoptotic signal by ceramide[J]. Chinese Bulletin of Life Sciences,2006,18(5):481-486. |
| APA | JIN DaoZhong,&ZHU XingZu.(2006).Regulation of metabolism and apoptotic signal by ceramide.Chinese Bulletin of Life Sciences,18(5),481-486. |
| MLA | JIN DaoZhong,et al."Regulation of metabolism and apoptotic signal by ceramide".Chinese Bulletin of Life Sciences 18.5(2006):481-486. |
入库方式： OAI收割
来源：上海药物研究所
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